Pulmonary Alveolar Proteinosis-Like Pathological Changes Mimicking Lung Adenocarcinoma in Situ.

IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Tohoku Journal of Experimental Medicine Pub Date : 2024-12-20 Epub Date: 2024-07-18 DOI:10.1620/tjem.2024.J064
Kazuki Hayasaka, Tomohiro Fujita, Shunsuke Eba, Nobuyuki Sato, Hidekachi Kurotaki, Chihiro Inoue
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引用次数: 0

Abstract

An enlarging ground-glass nodule (GGN) in the lungs closely resembles the characteristic appearance of a well differentiated lung adenocarcinoma or adenocarcinoma in situ (AIS). Herein, we present an unusual case characterized by clinical features suggestive of AIS but pathologically confirmed as exhibiting pulmonary alveolar proteinosis (PAP)-like changes. Patients with enlarging pure GGNs warrant consideration for diagnostic and curative surgery. While a considerable proportion of such cases receives a pathological diagnosis of lung malignancy, it is imperative to consider alternative benign conditions in the differential diagnosis, such as PAP-like changes.

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CiteScore
3.60
自引率
4.50%
发文量
171
审稿时长
1 months
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