The relentless right ear pain: A case report

Amy Davis, Gabriel Autry
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Abstract

Background

Fusobacterium necrophorum is an anaerobic gram-negative rod commonly found in humans' gastrointestinal and respiratory tracts. While classically associated with Lemierre's syndrome, F. necrophorum can cause pharyngitis, sinusitis, and otitis, especially in young adults. On rare occasions, it can progress to lifethreatening complications including meningitis, intracranial abscess, and sinus thrombosis.

Case Report

Case Report-An adolescent presented multiple times in one week for persistent right ear pain. Despite treatment, the patient continued to worsen and presented to the emergency department after developing fever, lethargy, and vomiting. Lumbar puncture confirmed meningitis with over 250 white blood cells x10∼3/UL. The patient was transferred to a children's hospital, where cavernous sinus thrombosis was also identified. The patient underwent mastoidectomy and started on heparin intravenously. Upon discharge, he transitioned to enoxaparin and later rivaroxaban for three months. Why should an emergency physician be aware of this? Fusobacterium necrophorum is a rare cause of otitis and meningitis but can be deadly if not treated appropriately. As a gram-negative anaerobe, standard meningitis treatment does not adequately treat this organism. Significant morbidity and mortality are associated with this disease.

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难以忍受的右耳疼痛病例报告
背景坏死杆菌是一种厌氧革兰阴性杆菌,常见于人类的胃肠道和呼吸道。虽然该病通常与莱米埃尔综合征有关,但它也可引起咽炎、鼻窦炎和中耳炎,尤其是在青壮年中。在极少数情况下,它会发展成脑膜炎、颅内脓肿和鼻窦血栓等危及生命的并发症。病例报告病例报告--一名青少年在一周内多次因持续性右耳疼痛就诊。尽管接受了治疗,但患者的病情持续恶化,并在出现发热、嗜睡和呕吐后到急诊科就诊。腰椎穿刺确诊为脑膜炎,白细胞超过 250 x10∼3/UL。患者被转到一家儿童医院,在那里还发现了海绵窦血栓。患者接受了乳突切除术,并开始静脉注射肝素。出院后,他转而使用依诺肝素,后来又使用利伐沙班三个月。急诊医生为什么要注意这一点?坏死杆菌是引起中耳炎和脑膜炎的一种罕见病原体,但如果治疗不当也可能致命。作为一种革兰氏阴性厌氧菌,标准的脑膜炎治疗方法并不能充分治疗这种病菌。这种疾病的发病率和死亡率都很高。
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