Optogenetic modulation of cardiac autonomic nervous system

IF 3.2 4区 医学 Q2 NEUROSCIENCES Autonomic Neuroscience-Basic & Clinical Pub Date : 2024-07-17 DOI:10.1016/j.autneu.2024.103199
Ramon A. Hernández-Domínguez , Jorge F. Herrera-Orozco , Guadalupe E. Salazar-Calderón , María Chávez-Canales , Manlio F. Márquez , Felipe González-Álvarez , Armando Totomoch-Serra , Tania Reyes-Cruz , Finn Lip , José J. Aceves-Buendía
{"title":"Optogenetic modulation of cardiac autonomic nervous system","authors":"Ramon A. Hernández-Domínguez ,&nbsp;Jorge F. Herrera-Orozco ,&nbsp;Guadalupe E. Salazar-Calderón ,&nbsp;María Chávez-Canales ,&nbsp;Manlio F. Márquez ,&nbsp;Felipe González-Álvarez ,&nbsp;Armando Totomoch-Serra ,&nbsp;Tania Reyes-Cruz ,&nbsp;Finn Lip ,&nbsp;José J. Aceves-Buendía","doi":"10.1016/j.autneu.2024.103199","DOIUrl":null,"url":null,"abstract":"<div><p>The following is a narrative review of the fundamentals of optogenetics. It focuses on the advantages and constraints of manipulating the autonomic nervous system by modifying the pathophysiological characteristics that arise in different diseases. Although the use of this technique is currently experimental, we will discuss improvements that have been implemented and identify the necessary measures for potential preclinical translation in the control of the cardiac autonomic nervous system.</p></div>","PeriodicalId":55410,"journal":{"name":"Autonomic Neuroscience-Basic & Clinical","volume":"255 ","pages":"Article 103199"},"PeriodicalIF":3.2000,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Autonomic Neuroscience-Basic & Clinical","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1566070224000535","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0

Abstract

The following is a narrative review of the fundamentals of optogenetics. It focuses on the advantages and constraints of manipulating the autonomic nervous system by modifying the pathophysiological characteristics that arise in different diseases. Although the use of this technique is currently experimental, we will discuss improvements that have been implemented and identify the necessary measures for potential preclinical translation in the control of the cardiac autonomic nervous system.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
光遗传学调节心脏自主神经系统
以下是对光遗传学基本原理的叙述性回顾。它侧重于通过改变不同疾病的病理生理特征来操纵自律神经系统的优势和限制因素。虽然这项技术的使用目前还处于实验阶段,但我们将讨论已经实施的改进措施,并确定必要的措施,以便在控制心脏自律神经系统方面实现潜在的临床前转化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
5.80
自引率
7.40%
发文量
83
审稿时长
66 days
期刊介绍: This is an international journal with broad coverage of all aspects of the autonomic nervous system in man and animals. The main areas of interest include the innervation of blood vessels and viscera, autonomic ganglia, efferent and afferent autonomic pathways, and autonomic nuclei and pathways in the central nervous system. The Editors will consider papers that deal with any aspect of the autonomic nervous system, including structure, physiology, pharmacology, biochemistry, development, evolution, ageing, behavioural aspects, integrative role and influence on emotional and physical states of the body. Interdisciplinary studies will be encouraged. Studies dealing with human pathology will be also welcome.
期刊最新文献
Sex differences in heart rate and heart rate variability responses to transcutaneous auricular vagal nerve stimulation in rats. Co-occurrence of Loeys-Dietz syndrome with postural orthostatic tachycardia syndrome: A case series Cardiovascular effects of early maternal separation and escitalopram treatment in rats with depressive-like behaviour Piezo1, but not ATP, is required for mechanotransduction by bladder mucosal afferents in cystitis. Metabolic targets in the Postural Orthostatic Tachycardia Syndrome: A short thematic review.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1