V. Chernyshev, Valentine P. Ananikov, K. Shepelenko, I. G. Gnatiuk, I. V. Lavrentev, M. E. Minyaev
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引用次数: 0
Abstract
A new approach for the preparation of a variety of 3-arylated 2-furoic acid derivatives has been developed. The approach involves selective Ru-catalyzed C3-H arylation of the furan moiety of readily available 2-furoyl-1-methylimidazole (using imidazole as a removable N-donor directing group), subsequent N-methylation, and nucleophilic substitution of the imidazole moiety with N, O, S, and C nucleophiles.
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