A Rare Case Report of Herpes Simplex Virus Encephalitis and Herpes Zoster Skin Lesion: Its Diagnosis and Treatment

Akshatha, Bharathi, Greeshma Raju, S. V. Naik, Syed Mohammed Hussaini
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Abstract

Herpes Simplex Virus (HSV) encephalitis and Herpes Zoster skin lesions are both caused by different strains of the herpes virus. Herpes Simplex Virus (HSV) encephalitis is caused by the Herpes Simplex Virus (HSV), typically HSV-1, while Herpes Zoster, commonly known as shingles, is caused by the Varicella-Zoster Virus (VZV), which is also a member of the herpesvirus family. This is a case report of HSVE with HZ in a 65 year’s old male patient admitted to hospital with chief complaints of erythematous fluid filled rash over abdomen since 1 week, two episodes of generalised type seizures involved all four limbs and with altered sensorium since 1 day. His past medical history revealed that he was a known case of pulmonary tuberculosis (PTB) 2 years ago and taken antitubercular therapy (ATT) for 6 months and also he had developed chickenpox in his childhood. The patient was diagnosed with herpes skin lesion and herpes simplex virus encephalitis based on his USG report and clinical, neurological symptoms respectively. His laboratory tests revealed abnormal haematology and LFT parameters, USG abdomen showed grade 1 fatty changes with hepatomegaly, echogenic sediments in urinary bladder and herpes zoster eruption in dermatomal distribution, chest X-ray showed suggestive sequalae of pulmonary Koch’s. the treatment was initiated with Acyclovir, Levetiracetam, Tramadol, etc.
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单纯疱疹病毒脑炎和带状疱疹皮损的罕见病例报告:诊断与治疗
单纯疱疹病毒(HSV)脑炎和带状疱疹皮损都是由不同的疱疹病毒株引起的。单纯疱疹病毒(HSV)脑炎是由单纯疱疹病毒(HSV)(通常是 HSV-1)引起的,而带状疱疹(俗称带状疱疹)是由水痘-带状疱疹病毒(VZV)引起的,后者也是疱疹病毒家族的一员。这是一例HSVE合并HZ的病例报告,患者是一名65岁的男性,入院时主诉腹部一周以来出现红斑性液状皮疹,两度全身型癫痫发作累及四肢,一天以来感觉改变。既往病史显示,他两年前曾患过肺结核(PTB),并接受过 6 个月的抗结核治疗(ATT),童年时还出过水痘。根据他的 USG 报告以及临床和神经系统症状,患者被诊断为疱疹性皮肤损伤和单纯疱疹病毒脑炎。他的实验室检查显示血液学和低密度脂蛋白血症参数异常,腹部 USG 显示 1 级脂肪病变伴肝脏肿大,膀胱内有回声沉积物,皮肤上有带状疱疹糜烂,胸部 X 光检查显示有肺科氏病的提示性后遗症。
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