Retroperitoneal laparoscopic radical nephrectomy in the treatment of renal cancer: a 5-year single-center experience in resource-scare setting

Nguyen Minh An, Ngo Trung Kiên, Nguyen Van Duc, Vo Hoang Long
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Abstract

Based on a retrospective hospital-based analysis, this study examines the results of retroperitoneal laparoscopic radical nephrectomy for patients with T1-T2 renal cell carcinoma (RCC) from January 2019 to December 2023. Of the 73 patients, 4.1% had TNM stage II tumors and 95.8% had TNM stage I tumors (53.4% T1a and 42.4% T1b). In terms of frequency, clear cell RCC accounted for 84.9%, with papillary RCC coming in at 9.6% and chromophobe RCC at 4.1%. Following surgery, four patients experienced fevers, one needed a blood transfusion, two had infections, and one had emergency surgery. Lumbar masses and hematuria were absent in all patients. Subsequent metastatic lesions and abnormalities of the renal fossa were not observed on follow-up ultrasounds. 4.1% of the deaths after 25.9 months were due to the disease, and 1.4% were caused by accidents. At one, two, three, and four years, the cumulative survival rates were 100%, 97.2%, and 92.8%, respectively. 48.1 months was the mean postoperative survival period. For RCC stages T1-2, retroperitoneal laparoscopic radical nephrectomy offers significant benefits and comparable results to open surgery.
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治疗肾癌的腹膜后腹腔镜根治性肾切除术:在资源匮乏的环境中进行的为期五年的单中心临床实践
本研究基于一项基于医院的回顾性分析,研究了2019年1月至2023年12月期间T1-T2肾细胞癌(RCC)患者的腹膜后腹腔镜根治性肾切除术的结果。在73名患者中,4.1%为TNM II期肿瘤,95.8%为TNM I期肿瘤(53.4%为T1a,42.4%为T1b)。就发病频率而言,透明细胞RCC占84.9%,乳头状RCC占9.6%,嗜色细胞RCC占4.1%。手术后,四名患者出现发热,一名患者需要输血,两名患者出现感染,一名患者进行了急诊手术。所有患者均无腰部肿块和血尿。在后续的超声波检查中未发现转移病灶和肾窝异常。在25.9个月后死亡的患者中,4.1%死于疾病,1.4%死于意外。1年、2年、3年和4年的累积存活率分别为100%、97.2%和92.8%。术后平均生存期为 48.1 个月。对于T1-2期的RCC,腹膜后腹腔镜根治性肾切除术具有显著的优势,效果与开放手术相当。
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