Medicinal Orchids of Mexico: A Review

Pharmaceuticals Pub Date : 2024-07-08 DOI:10.3390/ph17070907
Luis J. Castillo-Pérez, Amauri Ponce-Hernández, Á. Alonso-Castro, R. Solano, J. Fortanelli-Martínez, L. Lagunez-Rivera, Candy Carranza-Álvarez
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Abstract

Some species of the Orchidaceae family are used in Mexican traditional medicine. However, there are no current and critical compilations of the medicinal uses and pharmacological effects of the members of the Orchidaceae family. This review provides a current, critical, and comprehensive analysis of the traditional medicinal uses, pharmacological reports, and active compounds isolated from Mexican orchids. A total of 62 Mexican orchids with medicinal potential have been recorded, of which 14 have scientific evidence. The remaining 48 plant species have ethnomedicinal information but have not been validated with scientific studies. These orchids are distributed in 14 states of the Mexican Republic, mainly in the southern region of Mexico. The most common pharmacological activities reported are anti-inflammatory, vasorelaxant, antinociceptive, antioxidant, spasmolytic, antihypertensive, and hallucinogenic activities. It is necessary to increase the number of pharmacological, phytochemical, and toxicological studies with medicinal orchids from Mexico because there are scientific studies on only 22.5% of these species. In further studies, it will be possible to evaluate the pharmacological effects of Mexican orchids in clinical trials. In addition, the mechanisms of action by which plant extracts and their active compounds exert medicinal effects remain to be studied. Plant extracts from orchids and their active compounds show promising antinociceptive and spasmolytic effects, respectively.
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墨西哥的药用兰花:综述
墨西哥传统医学中使用了一些兰科植物。然而,目前还没有关于兰科植物的药用和药理作用的重要汇编。本综述对墨西哥兰花的传统药用价值、药理学报告以及从墨西哥兰花中分离出的活性化合物进行了最新、严谨和全面的分析。共有 62 种墨西哥兰花具有药用潜力,其中 14 种已有科学证据。其余 48 种植物有民族药用信息,但未经科学研究验证。这些兰花分布在墨西哥共和国的 14 个州,主要集中在墨西哥南部地区。据报道,最常见的药理活性是抗炎、舒张血管、抗痛觉、抗氧化、解痉、降压和致幻活性。有必要增加对墨西哥药用兰花进行药理学、植物化学和毒理学研究的数量,因为目前只对其中 22.5% 的物种进行了科学研究。在进一步的研究中,将有可能在临床试验中评估墨西哥兰花的药理作用。此外,植物提取物及其活性化合物发挥药效的作用机制仍有待研究。兰花的植物提取物及其活性化合物分别显示出良好的抗痛觉作用和解痉作用。
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