D-DIMER AS A PROGNOSIS OF THE SEVERITY OF COVID-19 PATIENTS AT BEKASI REGENCY HOSPITAL

Dyah Eka Kurniawati
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Abstract

The increase in D-dimer is the most significant change in coagulation parameters in Covid-19 patients and can be a marker of poor prognosis.  The purpose of this study was to see the average significant D-dimer levels in patients with confirmed Covid-19 with severity. The method used is Retrospective Research with a purposive sampling technique based on the criteria of the severity of Covid-19 disease. Patient data was taken from medical records and D-dimer levels from the Laboratory Information System and then analyzed using a one-way Anova test. The results showed an average D-dimer level of 2.66 mg/L at critical degrees, 2.02 mg/L at severe degrees, 0.30 at moderate degrees and 0.26 at mild degrees. Male patients occupy a larger percentage than female patients with a total of 62.5%. The age of 46-65 years occupies the highest percentage of 55% for the abnormal category because the immune system as a protector of the body does not work as strongly as when it was young. This study showed a significant average difference in the groups of mild severity with severe, mild with critical, moderate with severe, and moderate with critical. For the next researcher, it is expected to be able to analyze other hemostasis examination parameters with variables of disease severity. Kata kunci: Coronavirus, COVID-19, D-dimer, parameter koagulasi, pembekuan darah
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D-二聚体作为勿加泗Regency医院Covid-19患者严重程度的预后指标
D 二聚体的增加是 Covid-19 患者凝血指标中最显著的变化,也是预后不良的标志。 本研究的目的是了解确诊的 Covid-19 患者的 D-二聚体平均显著水平与严重程度的关系。采用的方法是回顾性研究,根据 Covid-19 疾病的严重程度标准采用目的性抽样技术。患者数据来自病历,D-二聚体水平来自实验室信息系统,然后使用单因子Anova检验进行分析。结果显示,临界程度的 D-二聚体平均水平为 2.66 毫克/升,重度为 2.02 毫克/升,中度为 0.30 毫克/升,轻度为 0.26 毫克/升。男性患者的比例高于女性患者,共占 62.5%。46-65 岁年龄段的异常人群占比最高,达到 55%,这是因为作为身体保护者的免疫系统已不像年轻时那样强大。这项研究显示,轻度严重与重度、轻度与临界、中度与重度、中度与临界组的平均差异很大。对于下一位研究人员来说,有望能够分析其他止血检查参数与疾病严重程度的变量。 Kata kunci: Coronavirus, COVID-19, D-dimer, parameter koagulasi, pembekuan darah
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