{"title":"Missed rifampicin and isoniazid resistance by commercial molecular assays","authors":"L. Richards, F. Ismail, J. Nel, S. V. Omar","doi":"10.7196/samj.2024.v114i17.1779","DOIUrl":null,"url":null,"abstract":"\n\n\n\nDrug-resistant tuberculosis (TB) has poor outcomes unless resistance is detected early, ideally by commercially available molecular tests. We present a case of occult multidrug-resistant TB where both rifampicin and isoniazid resistance were missed by molecular testing and were only identified by phenotypic testing.\n\n\n\n","PeriodicalId":22034,"journal":{"name":"South African Medical Journal","volume":"11 8","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"South African Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7196/samj.2024.v114i17.1779","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Drug-resistant tuberculosis (TB) has poor outcomes unless resistance is detected early, ideally by commercially available molecular tests. We present a case of occult multidrug-resistant TB where both rifampicin and isoniazid resistance were missed by molecular testing and were only identified by phenotypic testing.
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