Neuromolecular analysis of post-traumatic stress disorder – the dysregulation in neuronal and signalling pathways

Q4 Biochemistry, Genetics and Molecular Biology Medical Journal of Cell Biology Pub Date : 2024-07-01 DOI:10.2478/acb-2024-0003
Livhuwani Nesengani, Vanessa Andrine Sherington, Chloe Snaifer
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Abstract

Abstract Post-traumatic stress disorder (PTSD) is a mental disorder as a result of life-threatening situations which in turn affects quality of life through activities of daily living. This is attributed to a plethora of neuromolecular factors negatively affecting the functional make-up of the brain. The complex interplay of these factors include neuronal alterations and neuroplasticity, signalling molecular, astrocyte and glial cell alterations which together act as a survival mechanism in several brain regions.
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创伤后应激障碍的神经分子分析--神经元和信号通路的失调
摘要 创伤后应激障碍(PTSD)是一种因生命受到威胁而导致的精神障碍,进而影响日常生活质量。这归因于对大脑功能构成产生负面影响的大量神经分子因素。这些因素之间复杂的相互作用包括神经元的改变和神经可塑性、信号分子、星形胶质细胞和胶质细胞的改变,它们共同作用于多个脑区的生存机制。
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来源期刊
Medical Journal of Cell Biology
Medical Journal of Cell Biology Biochemistry, Genetics and Molecular Biology-Cell Biology
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