Active offer of Tdap vaccination in a cohort of healthcare workers of Maternal and Neonatal Department: Data from a large hospital in Southern Italy

IF 2.7 Q3 IMMUNOLOGY Vaccine: X Pub Date : 2024-07-18 DOI:10.1016/j.jvacx.2024.100530
Antonio Di Lorenzo , Luca Capodiferro , Michele Illuzzi , Chiara Scaltrito , Luigi Vimercati , Lorenza Moscara , Silvio Tafuri , Pasquale Stefanizzi
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Abstract

Pertussis is a vaccine-preventable respiratory disease. Pertussis vaccination is currently mandatory for all children in Italy, and is administered in three doses at the beginning of the third, fifth, and twelfth month of life, respectively. Booster doses are also recommended at five-six years, at eleven-twelve years, and then once every ten years. Healthcare workers (HCWs) are a high-risk population for pertussis. Strategies to increase HCWs’ compliance to this vaccination have not been investigated in depth. Our study investigates the determinants of acceptance of a “soft nudge” vaccination campaign in a large hospital in Apulia (Southern Italy).

HCWs from the Gynaecology and Neonatology Units of Bari’s Policlinico General Hospital were screened in June 2023 for pertussis vaccination. Non-vaccinated subjects were offered a vaccination appointment. Vaccination determinants were studied, and a logistic regression model was built to identify determinants that significantly influence vaccination acceptance.

At the time of screening, only 31.34% of target HCWs (68/217) had already been vaccinated. After the active call intervention, vaccine coverage rose to 70.00% (152/217). Significantly higher coverage was found in the Neonatology Unit (30/43, 69.77%) than in the Gynaecology unit (54/106, 50.94%) (Chi2: 4.41; p-value: 0.036). A logistic regression model confirmed a higher compliance to vaccination in HCWs staffed in the Neonatology Unit (Chi2: 2.08; 95%CI: 1.04 – 4.73; p-value: 0.038).

Our intervention increased vaccination coverage in a high-risk cohort. The solicitation was effective, as communication with a trained specialist might have improved the subjects’ perception of vaccination and individual risk of contagion and transmission to others. A synergistic approach, mixing active call with a vaccination mandate, might have greater effectiveness.

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在孕产妇和新生儿科医护人员中积极开展百白破疫苗接种:来自意大利南部一家大型医院的数据
百日咳是一种可通过疫苗预防的呼吸道疾病。目前,意大利所有儿童都必须接种百日咳疫苗,分别在出生后第三个月、第五个月和第十二个月开始时接种三次。此外,还建议在 5-6 岁、11-12 岁时接种加强剂,然后每十年接种一次。医护人员是百日咳的高危人群。提高医护人员接种疫苗依从性的策略尚未得到深入研究。我们的研究调查了阿普利亚(意大利南部)一家大型医院接受 "软劝导 "疫苗接种活动的决定因素。2023 年 6 月,我们对巴里 Policlinico 综合医院妇科和新生儿科的医护人员进行了百日咳疫苗接种筛查。未接种者可预约接种。对疫苗接种的决定因素进行了研究,并建立了一个逻辑回归模型,以确定对疫苗接种接受度有显著影响的决定因素。在筛查时,只有 31.34% 的目标医护人员(68/217)已经接种了疫苗。在主动呼叫干预后,疫苗接种覆盖率上升到 70.00%(152/217)。新生儿科的覆盖率(30/43,69.77%)明显高于妇科(54/106,50.94%)(Chi2:4.41;P 值:0.036)。逻辑回归模型证实,新生儿科的医护人员接种疫苗的依从性更高(Chi2:2.08;95%CI:1.04 - 4.73;P 值:0.038)。我们的干预措施提高了高风险人群的疫苗接种率。邀请接种是有效的,因为与训练有素的专家交流可能会提高受试者对疫苗接种的认识,以及个人感染和传染他人的风险。将积极号召与疫苗接种任务相结合的协同方法可能会产生更大的效果。
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来源期刊
Vaccine: X
Vaccine: X Multiple-
CiteScore
2.80
自引率
2.60%
发文量
102
审稿时长
13 weeks
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