Improved Patient Adherence to Family-Based Helicobacter pylori Infection Control and Management Strategy in Central China and Its Influencing Factors

IF 4.3 2区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY Helicobacter Pub Date : 2024-07-19 DOI:10.1111/hel.13114

Xiao-Ting Li, Lu Xu, Chen Zhang, Ya-Bin Qi, Ruo-Bing Hu, Mohammed Awadh Abdun, Xue-Chun Yu, Kuan Li, Ting-Ting Liu, Jing Ma, Wei Xiao, Ling Lan, Xue-Mei Wang, Ming-Bo Cao, Jian Li, Shuang-Yin Han, Xiu-Ling Li, Song-Ze Ding

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Abstract

Background

Patient adherence status to the newly introduced family-based Helicobacter pylori (H. pylori) infection control and management strategy remains unclear, so are its influencing factors. We aim to investigate family members' adherence and its influencing factors during the family-based H. pylori infection management practice for related disease prevention.

Materials and Methods

Based on our previously family-based H. pylori survey in 2021, 282 families including 772 individuals were followed up 2 years after the initial survey to compare if the investigation and education might improve family member's adherence. The participant's adherence to H. pylori infection awareness, retest, treatment, publicity, gastroscopy, and hygiene habits were followed up, and their influencing factors were also analyzed.

Results

The overall participant's adherence to recommendations on H. pylori awareness, retest, treatment, publicity, gastroscopy, and hygiene habits were 77% (187/243), 67.3% (138/205), 60.1% (211/351), 46.5% (107/230), 45.6% (159/349), and 39.1% (213/545), respectively; and all showed improvements compared with their prior survey stages. The top reasons for rejection to treatment, retest, and gastroscopy were forgetting or unaware of H. pylori infection (30.3%), busy (32.8%), and asymptomatic (67.9%), respectively. Independent risk factor for low adherence to treatment was occupation (e.g., staff: OR 4.49, 95% CI 1.34–15.10). Independent favorable factors for treatment adherence were individuals at the ages of 18–44 years (OR 0.19, 95% CI 0.04–0.89) and had a large family size (e.g., four family members: OR 0.15, 95% CI 0.06–0.41); for retest adherence, it was individuals at the ages of 60–69 years (OR 0.23, 95% CI 0.06–0.97); for gastroscopy adherence, it was individuals at the age of 60–69 years (OR 0.46, 95% CI 0.28–0.75), and with gastrointestinal symptoms (OR 0.57, 95% CI 0.36–0.90).

Conclusions

Family-based H. pylori management increases individual adherence to treatment, retest, and awareness, and there are also improved adherence to gastroscopy, publicity, and personal hygiene recommendations; further efforts are required to enhance the individual adherence rate for related disease prevention.

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中国中部地区幽门螺杆菌感染控制和管理策略的家庭式患者依从性改善及其影响因素。

背景：患者对新引入的基于家庭的幽门螺杆菌（H. pylori）感染控制和管理策略的依从性状况仍不清楚，其影响因素也不清楚。我们旨在调查在基于家庭的幽门螺杆菌感染管理实践中家庭成员的依从性及其影响因素，以预防相关疾病：在 2021 年开展的基于家庭的幽门螺杆菌调查的基础上，我们在首次调查后 2 年对 282 个家庭（包括 772 人）进行了随访，以比较调查和教育是否能提高家庭成员的依从性。对参与者对幽门螺杆菌感染的认知、复检、治疗、宣传、胃镜检查和卫生习惯的依从性进行了跟踪调查，并对其影响因素进行了分析：结果：总体受试者对幽门螺杆菌感染认知、复检、治疗、宣传、胃镜检查和卫生习惯建议的依从性分别为 77%（187/243）、67.3%（138/205）、60.1%（211/351）、46.5%（107/230）、45.6%（159/349）和 39.1%（213/545），与之前的调查阶段相比均有所改善。拒绝治疗、复检和胃镜检查的首要原因分别是忘记或不知道幽门螺杆菌感染（30.3%）、忙碌（32.8%）和无症状（67.9%）。职业是导致治疗依从性低的独立危险因素（如工作人员：OR 4.49，95% CI 1.34-15.10）。坚持治疗的独立有利因素是年龄在 18-44 岁（OR 值为 0.19，95% CI 值为 0.04-0.89）和家庭人口多（例如：四个家庭成员：OR 值为 0.15，95% CI 值为 0.04-0.89）、复检依从性方面，年龄在 60-69 岁的人群（OR 值为 0.23，95% CI 为 0.06-0.97）；胃镜检查依从性方面，年龄在 60-69 岁的人群（OR 值为 0.46，95% CI 为 0.28-0.75）以及有胃肠道症状的人群（OR 值为 0.57，95% CI 为 0.36-0.90）：以家庭为基础的幽门螺杆菌管理提高了个人对治疗、复检和认知的依从性，同时也提高了对胃镜检查、宣传和个人卫生建议的依从性；需要进一步努力提高个人对相关疾病预防的依从性。

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来源期刊

Helicobacter 医学-微生物学

CiteScore

8.40

自引率

9.10%

发文量

审稿时长

2 months

期刊介绍： Helicobacter is edited by Professor David Y Graham. The editorial and peer review process is an independent process. Whenever there is a conflict of interest, the editor and editorial board will declare their interests and affiliations. Helicobacter recognises the critical role that has been established for Helicobacter pylori in peptic ulcer, gastric adenocarcinoma, and primary gastric lymphoma. As new helicobacter species are now regularly being discovered, Helicobacter covers the entire range of helicobacter research, increasing communication among the fields of gastroenterology; microbiology; vaccine development; laboratory animal science.