Superficial and Invasive Spread of High-grade Squamous Intraepithelial Lesion and Squamous Cell Carcinoma: A Case Report.

IF 1.6 4区 医学 Q3 OBSTETRICS & GYNECOLOGY International Journal of Gynecological Pathology Pub Date : 2024-07-22 DOI:10.1097/PGP.0000000000001062
Dan T Nguyen, Dale Waring, King M Wan, Christine Loo
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Abstract

We present a case of extensive spread of high-grade squamous intraepithelial lesion (HSIL)/cervical intraepithelial neoplasia grade 3 (CIN3) with foci of invasive squamous cell carcinoma (SCC) in a premenopausal woman. Superficial spread of CIN3 and cervical SCC to the endometrium and/or fallopian tubes is rare, especially in countries with cervical cancer screening programs. Our case occurred during the COVID-19 pandemic, which may have been a major contributing factor to delayed detection and, consequently extensive spread.

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高级别鳞状上皮内病变和鳞状细胞癌的表皮和浸润性扩散:病例报告。
我们介绍了一例绝经前妇女高级别鳞状上皮内病变(HSIL)/宫颈上皮内瘤变 3 级(CIN3)广泛扩散并伴有浸润性鳞状细胞癌(SCC)病灶的病例。CIN3 和宫颈 SCC 表皮扩散至子宫内膜和/或输卵管的情况很少见,尤其是在开展宫颈癌筛查项目的国家。我们的病例发生在 COVID-19 大流行期间,这可能是导致该病被延迟发现并进而大面积扩散的一个主要因素。
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来源期刊
CiteScore
3.90
自引率
12.50%
发文量
154
审稿时长
6-12 weeks
期刊介绍: International Journal of Gynecological Pathology is the official journal of the International Society of Gynecological Pathologists (ISGyP), and provides complete and timely coverage of advances in the understanding and management of gynecological disease. Emphasis is placed on investigations in the field of anatomic pathology. Articles devoted to experimental or animal pathology clearly relevant to an understanding of human disease are published, as are pathological and clinicopathological studies and individual case reports that offer new insights.
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