Giant solitary fibrous tumor of the olfactory groove. An unusual simulator in an unusual location

Fernando García Pérez , Ascensión Contreras Jiménez , Beatriz Agredano Ávila , José Masegosa González
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Abstract

Solitary fibrous tumors are rare mesenchymal neoplasms that can develop in any part of the body, with those that settle intracranially being confused with meningiomas as a general rule. We present the case of a 57-year-old man referred to our hospital due to bifrontal headache, anosmia, and behavioral alterations of 6 months' duration. Radiological studies revealed the existence of a large tumor mass with an extra-axial appearance and location in the anterior cranial fossa, initially compatible with a giant meningioma of the olfactory groove. Gross total resection of the mass was carried out. The pathological diagnosis was unexpected: a solitary fibrous tumor (WHO grade 1, 2021). Given the aggressive nature of these lesions, with a tendency to recurrence, malignant transformation and even metastasis, surgery with macroscopically complete resection intention should constitute the first therapeutic option. Close clinical-radiological follow-up after the procedure is justified.
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嗅沟巨型单发纤维瘤。不寻常位置的不寻常模拟器。
孤立性纤维瘤是一种罕见的间叶肿瘤,可发生在身体的任何部位,颅内的孤立性纤维瘤通常会与脑膜瘤相混淆。本病例是一名 57 岁的男性,因双额叶头痛、嗅觉障碍和行为改变而转诊至我院,病程长达 6 个月。放射学检查显示,患者颅前窝存在一个轴外外观的巨大肿瘤肿块,初步诊断为嗅沟巨大脑膜瘤。医生对肿块进行了全切。病理诊断出乎意料:单发纤维瘤(世卫组织 1 级,2021 年)。鉴于此类病变具有侵袭性,容易复发、恶变甚至转移,因此应首先选择大体上完全切除的手术治疗。术后应进行密切的临床和放射学随访。
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