Eucalyptus emulgel: A novel formulation with analgesic properties

Aditi Anand Kasture, Vaishnavi Shrinivas Gone, Rakesh Rajshekhar Gore
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Abstract

Emulgels have emerged as a promising topical drug delivery system for the delivery of hydrophobic drug via skin. The objective of the study was to prepare eucalyptus emulgel. When we are preparing a emulsion individually shows stability problems during manufacturing and storage that effects on drug release pattern. In order to increase the drug stability, we incorporate it as emulgel. Emulgel is a thermodynamically stable formulation with low interfacial tension that is made by combining a surfactant and a co-surfactant and has several properties such as increased permeability and good thermodynamic stability. Emulgel has a dual control and a sustained release pattern. Emulgel improves bioavailability as well as patient compliance. This emulgel prepared as an analgesic, which satisfies all the testing parameters. The emulgel was produced in various batches of which F3 if found to be effective one.
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桉树凝胶:具有镇痛特性的新型配方
在通过皮肤输送疏水性药物方面,乳胶已成为一种前景广阔的局部给药系统。这项研究的目的是制备桉树乳胶。当我们制备乳液时,在生产和储存过程中会出现稳定性问题,从而影响药物的释放模式。为了提高药物的稳定性,我们将其制成了乳胶。乳胶凝胶是一种热力学稳定的制剂,具有较低的界面张力,由表面活性剂和辅助表面活性剂混合制成,具有多种特性,如渗透性增加和良好的热力学稳定性。Emulgel 具有双重控制和持续释放模式。Emulgel 提高了生物利用度和患者的依从性。这种镇痛凝胶符合所有测试参数。已生产出不同批次的镇痛凝胶,其中 F3 为有效批次。
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