Steatocystoma Multiplex Suppurativa Treated Successfully with Adalimumab and Topical Tofacitinib

Mariana McCune, Aaron Graff, Christina Harview, Lindsay Ackerman
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Abstract

Steatocystoma multiplex (SM) is a rare chronic dermatologic condition which may cause significant distress and negatively impact quality of life. Currently, there is no consensus for treatment. When inflammatory, it is called steatocystoma multiplex suppurativa, an even more rare condition that has shown reported success with anti-TNF-alpha therapy. We describe a patient case wherein adalimumab prescribed for autoimmune arthritis resulted in SMS remission, further supported with evidence of sustained remission with topical tofacitinib. This patient case supports other evidence showing adalimumab as a treatment option for SMS and highlights the potential of tofacitinib as a novel treatment.
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阿达木单抗和外用托法替尼成功治疗多发性湿性脂肪囊肿
多发性脂肪囊肿(SM)是一种罕见的慢性皮肤病,可能会给患者带来极大的痛苦,并对生活质量产生负面影响。目前,治疗方法尚未达成共识。当出现炎症时,它被称为多发性化脓性脂肪囊肿,这是一种更为罕见的疾病,有报道称抗 TNF-α 治疗取得了成功。我们描述了一例患者的病例,该患者因阿达木单抗治疗自身免疫性关节炎而导致 SMS 缓解,并有证据显示局部使用托法替尼后病情持续缓解。该病例支持其他证据显示阿达木单抗是治疗SMS的一种选择,并强调了托法替尼作为一种新型疗法的潜力。
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