Plant-derived exosomes: A Green Nanomedicine for Cancer

Swarup Sonar, Krishnan Anand
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Abstract

Exosomes are signalling molecules related to cell-to-cell communication. Based on sources (plants, stem cells, and immune cells derived exosomes) it offers promising therapeutic activity against cancer. Plant-derived exosomes (PDEs) are natural extracellular vesicles (EVs) that are potent to provide organic precision nanomedicine to cancer therapeutics including targeted drug delivery. PDEs are gaining attention due to their safety and efficacy. There are plenty of different sources of PDEs in nature. This article explores various plants such as carrots, ginger, lemons, cabbages, blueberries, oranges, tomatoes, grapefruits, and tea leaves, which provide exosomes with distinct therapeutic properties, including anti-inflammatory, antioxidant, and anticancer activities. PDEs exhibit significant potential in drug delivery. Ongoing research and clinical trials predict that PDEs will become effective, and affordable solutions for cancer treatment.

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植物外泌体:治疗癌症的绿色纳米药物
外泌体是与细胞间通信有关的信号分子。根据其来源(植物、干细胞和免疫细胞衍生的外泌体),它对癌症具有良好的治疗活性。植物提取的外泌体(PDEs)是天然的细胞外囊泡(EVs),可为癌症治疗提供有机的精准纳米药物,包括靶向给药。PDEs 因其安全性和有效性而备受关注。自然界中存在大量不同来源的 PDEs。本文探讨了胡萝卜、生姜、柠檬、卷心菜、蓝莓、橘子、西红柿、葡萄柚和茶叶等多种植物,它们提供的外泌体具有独特的治疗特性,包括抗炎、抗氧化和抗癌活性。PDEs 在药物输送方面具有巨大潜力。正在进行的研究和临床试验预测,多肽二醇将成为治疗癌症的有效且负担得起的解决方案。
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