Sinjini Datta, R. Pal, Y. Pal, Mnvl Chaitanya, Preeti Srivastava
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引用次数: 0
Abstract
The purpose of this study is to evaluate hyaluronic acid (HA), sometimes referred to as
hyaluronan or hyaluronate, as well as its derivatives and how they are used in cosmetic formulations.
N-acetylglucosamine and D-glucuronic acid are the two disaccharides that make up HA, a glycosaminoglycan that was first isolated from the vitreous humor of the eye and then found in other tissues
and fluids, including the synovial fluid and articular cartilage. It is found in all vertebrates, including
humans, and has a variety of roles in biological processes, such as wound healing, inflammation, cell
differentiation, and embryological development. With its moisturizing and anti-aging properties, HA
offers numerous advantages over other chemicals used in skin regeneration. The biological activity
and skin penetration of HA are influenced by its molecular weight. The current study outlines the key
elements of hyaluronic acid's usage in cosmetology, given its broad range of uses and applications in
ophthalmology, arthrology, pneumology, rhinology, aesthetic medicine, cancer, nutrition, and cosmetics. There is a discussion of the biological impact of HA at the skin's level as well as any possible
negative consequences. From the brand portfolios of the most well-known manufacturers, a few readily available cosmetic items containing HA have been discovered, and their composition has been
assessed.
本研究的目的是评估透明质酸(HA),有时也称为透明质酸或玻尿酸,以及其衍生物和它们在化妆品配方中的使用情况。N-乙酰葡糖胺和D-葡糖酸是构成HA的两种二糖,HA是一种糖胺聚糖,最早从眼睛的玻璃体中分离出来,然后在滑液和关节软骨等其他组织和液体中发现。它存在于包括人类在内的所有脊椎动物体内,在伤口愈合、炎症、细胞分化和胚胎发育等生物过程中发挥着多种作用。HA 具有保湿和抗衰老的特性,与其他用于皮肤再生的化学物质相比,HA 具有众多优势。HA 的生物活性和皮肤渗透性受其分子量的影响。鉴于透明质酸在眼科、关节科、肺科、鼻科、美容医学、癌症、营养和化妆品等领域的广泛用途和应用,本研究概述了透明质酸在美容学中应用的关键要素。此外,还讨论了 HA 在皮肤层面的生物影响以及任何可能的负面影响。从最知名的制造商的品牌组合中,我们发现了一些含有 HA 的现成化妆品,并对其成分进行了评估。
期刊介绍:
Current Drug Therapy publishes frontier reviews of high quality on all the latest advances in drug therapy covering: new and existing drugs, therapies and medical devices. The journal is essential reading for all researchers and clinicians involved in drug therapy.