Ok Hyung Nam, Tae-Young Park, Seo-Rin Jeong, Jonghyun Shin, Myeong-Kwan Jih
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引用次数: 0
Abstract
Fluoride-releasing adhesive tapes have been developed as a new fluoride delivery agent. However, application as caries prevention agents remains underexplored. This study aimed at evaluating the antimicrobial activity of two fluoride-releasing adhesive tapes against S. mutans biofilm. Two polyvinyl alcohol (PVA) tapes were investigated: (i) a fluoride-PVA (F-PVA) tape, (ii) a pullulan incorporated F-PVA (PF-PVA) tape. S. mutan strains were cultured and treated with the tapes. Antimicrobial effects were evaluated using the agar diffusion test, field-emission scanning electron microscopy (FE-SEM), and confocal laser scanning microscopy (CLSM). F-PVA tapes showed higher inhibition-zone diameters than PF-PVA at 48 h and 72 h. However, there were no significant differences (p > 0.05) between the effects of F-PVA and PF-PVA. The bio-volume of S. mutans and extracellular polymeric substances significantly decreased in the F-PVA tapes than in the PF-PVA tapes (p < 0.05). FE-SEM micrographs revealed less S. mutans colonization in F-PVA. F-PVA exhibited better antimicrobial activity against S. mutans than PF-PVA.
期刊介绍：
The purpose of The Journal of Clinical Pediatric Dentistry is to provide clinically relevant information to enable the practicing dentist to have access to the state of the art in pediatric dentistry.
From prevention, to information, to the management of different problems encountered in children''s related medical and dental problems, this peer-reviewed journal keeps you abreast of the latest news and developments related to pediatric dentistry.
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