Sign of Leser-Trélat Associated with Kaposi Sar-coma in an Immunocompetent Man.

Skinmed Pub Date : 2024-08-02 eCollection Date: 2024-01-01
Hershel E Dobkin, Juan P Estrada, Allen Sapadin, Nardin Awad
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Abstract

A 68-year-old Latino man presented at our clinic with asymptomatic, indurated red nodules and macules of 2-month duration on the left arm, forearm, and palm (Figure 1). Performed punch biopsy presented characteristic -features of Kaposi sarcoma (KS). Immunohistochemistry was positive for human herpesvirus 8 (HHV8), a highly correlated viral marker, confirming the diagnosis of KS (Figure 2). He was referred to oncology for further management, where he was found to be fully immunocompetent with a negative assessment of human immunodefi-ciency virus (HIV). Computed tomography (CT) performed of his chest and abdomen revealed no involvement of internal organs.

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一名免疫功能正常男子的莱瑟-特雷拉征兆与卡波西肉瘤有关
一名 68 岁的拉丁裔男子因左臂、前臂和手掌出现无症状、化脓性红色结节和斑丘疹就诊,病程 2 个月(图 1)。穿刺活检显示出卡波济肉瘤(KS)的特征。免疫组化结果显示人类疱疹病毒 8(HHV8)阳性,这是一种高度相关的病毒标记物,从而确诊为 KS(图 2)。他被转到肿瘤科接受进一步治疗,结果发现他的免疫功能完全正常,人类免疫缺陷病毒(HIV)检测呈阴性。对他的胸部和腹部进行的计算机断层扫描(CT)显示,内脏器官没有受累。
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