DMP-1 expression in alveolar bone socket following Anredera cordifolia (Ten.) Steenis treatment: A histological study.

IF 1.5 Q3 AGRICULTURE, DAIRY & ANIMAL SCIENCE Journal of Advanced Veterinary and Animal Research Pub Date : 2024-06-06 eCollection Date: 2024-06-01 DOI:10.5455/javar.2024.k775

Christian Khoswanto, Ira Kusuma Dewi

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Abstract

Objective: The study aimed to ascertain how Anredera cordifolia (Ten.) Steenis Gel affects the expression of protein dentin matrix protein-1 (DMP-1) in alveolar Wistar rats after tooth extraction.

Materials and methods: Rats were given A. cordifolia (Ten.) Steenis gel was in the socket after tooth extraction, and then the wound was sutured. The rats were sacrificed for 8 and 15 days following tooth extraction. The results on the 8^th and 15^th days demonstrate that the expression of DMP-1 in the treatment group is significantly higher than in the control group.

Results: Expression of DMP-1 in the socket after tooth extraction on days 8 and 15 with a 400x magnification light microscope in both of the A. cordifolia (Ten.) Steenis gel treatment groups showed significant differences compared to the control group.

Conclusion: The use of A. cordifolia (Ten.) Steenis gel can stimulate DMP-1 expression in alveolar bone after tooth extraction.

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Anredera cordifolia (Ten.) Steenis 治疗后牙槽骨中 DMP-1 的表达：组织学研究。

研究目的本研究的目的是弄清Anredera cordifolia (Ten.) Steenis凝胶如何影响拔牙后牙槽骨Wistar大鼠的蛋白质牙本质基质蛋白-1（DMP-1）的表达：大鼠拔牙后在牙槽窝内涂抹 A. cordifolia (Ten.) Steenis 凝胶，然后缝合伤口。拔牙后第 8 天和第 15 天牺牲大鼠。第 8 天和第 15 天的结果表明，治疗组 DMP-1 的表达明显高于对照组：结果：在拔牙后第 8 天和第 15 天，用 400 倍放大光镜观察，A. cordifolia (Ten.) Steenis 凝胶治疗组和对照组的 DMP-1 在牙槽窝中的表达均有明显差异：结论：使用 A. cordifolia (Ten.) Steenis 凝胶可刺激拔牙后牙槽骨中 DMP-1 的表达。

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来源期刊

Journal of Advanced Veterinary and Animal Research Veterinary-Veterinary (all)

CiteScore

2.70

自引率

7.10%

发文量

审稿时长

6 weeks

期刊介绍： Journal of Advanced Veterinary and Animal Research (JAVAR) - is an open access, international, peer-reviewed, quarterly, highly-indexed scientific journal publishing original research findings and reviews on all aspects of veterinary and animal sciences. Basic and applied researches on- - Anatomy & histology - Animal health economics - Animal nutrition - Animal reproduction - Animal science - Antimicrobial resistance (AMR) - Biochemistry - Biotechnology - Dairy science - Epidemiology - Food hygiene and technology - Genetics and breeding - Immunology - Microbiology - Parasitology - Pathology - Pharmacology & toxicology - Physiology - Poultry science - Preventive veterinary medicine - Public health - Surgery & obstetrics - Veterinary extension studies - Wildlife & aquatic medicine - Zoo animal medicine.