The incidence of acute pancreatitis with GLP-1 receptor agonist therapy in individuals with a known history of pancreatitis

IF 6.1 3区 医学 Q1 ENDOCRINOLOGY & METABOLISM Diabetes research and clinical practice Pub Date : 2024-08-05 DOI:10.1016/j.diabres.2024.111806
Laura D Lomeli , Alimitha M Kodali , Yumiko Tsushima , Adi E Mehta , Kevin M Pantalone
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Abstract

Glucagon-like peptide-1 receptor agonists (GLP-1RA) have been reported to increase the risk of acute pancreatitis (AP). This real-world study did not observe a higher frequency of AP with GLP-1RA exposure in adults with T2D and a prior history of AP regardless of etiology.

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已知有胰腺炎病史的人接受 GLP-1 受体激动剂治疗后的急性胰腺炎发病率。
据报道,胰高血糖素样肽-1 受体激动剂(GLP-1RA)会增加急性胰腺炎(AP)的风险。在这项真实世界研究中,并未观察到患有 T2D 且既往有急性胰腺炎病史的成人(无论病因如何)在接触 GLP-1RA 后发生急性胰腺炎的频率更高。
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来源期刊
Diabetes research and clinical practice
Diabetes research and clinical practice 医学-内分泌学与代谢
CiteScore
10.30
自引率
3.90%
发文量
862
审稿时长
32 days
期刊介绍: Diabetes Research and Clinical Practice is an international journal for health-care providers and clinically oriented researchers that publishes high-quality original research articles and expert reviews in diabetes and related areas. The role of the journal is to provide a venue for dissemination of knowledge and discussion of topics related to diabetes clinical research and patient care. Topics of focus include translational science, genetics, immunology, nutrition, psychosocial research, epidemiology, prevention, socio-economic research, complications, new treatments, technologies and therapy.
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