A suspected case of "itai-itai disease" in a cadmium-polluted area in Akita prefecture, Japan.

IF 4 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Environmental Health and Preventive Medicine Pub Date : 2024-01-01 DOI:10.1265/ehpm.24-00063

Toru Sasaki, Hyogo Horiguchi, Takehisa Matsukawa, Momoko Kobayashi, Yuki Omori, Etsuko Oguma, Atsushi Komatsuda

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Abstract

Background: Itai-itai disease is the most severe case of chronic cadmium (Cd) toxicity, which was endemic in Cd-polluted areas in the Jinzu River basin in Toyama prefecture, Japan. Akita prefecture also has Cd-polluted areas, but there have been no cases of "itai-itai disease".

Case presentation: An elderly female farmer with Cd nephropathy residing in a Cd-polluted area in the northern part of the Akita prefecture was identified through hospital-based screening at Akita Rosai Hospital in Odate city. She had chronic renal failure with a high Cd exposure level and advanced renal tubular dysfunction. The shortening of height, bone deformities and fractures, abnormal bone metabolism suggesting osteomalacia, and renal anemia were also noted. Therefore, "itai-itai disease", similar to cases in the Jinzu River basin, was suspected.

Conclusion: This is the first case of "itai-itai disease" in a Cd-polluted area in Akita prefecture.

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日本秋田县镉污染区的疑似 "itai-itai 病 "病例。

背景：伊泰伊泰病是慢性镉（Cd）中毒最严重的病例，流行于日本富山县神通川流域的镉污染区。秋田县也有镉污染地区，但没有 "itai-itai 病 "病例：病例介绍：通过大馆市秋田罗赛医院的医院筛查，发现一名居住在秋田县北部镉污染地区的老年女性农民患有镉肾病。她患有慢性肾衰竭，镉暴露水平高，肾小管功能障碍已到晚期。此外，她还出现身高缩短、骨骼畸形和骨折、骨代谢异常（提示骨软化症）和肾性贫血。因此，疑似 "itai-itai 病"，与晋祖河流域的病例相似：结论：这是秋田县镉污染地区的首例 "itai-itai 病"。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Environmental Health and Preventive Medicine PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH -

CiteScore

7.90

自引率

2.10%

发文量

审稿时长

10 weeks

期刊介绍： The official journal of the Japanese Society for Hygiene, Environmental Health and Preventive Medicine (EHPM) brings a comprehensive approach to prevention and environmental health related to medical, biological, molecular biological, genetic, physical, psychosocial, chemical, and other environmental factors. Environmental Health and Preventive Medicine features definitive studies on human health sciences and provides comprehensive and unique information to a worldwide readership.