Rebecca Piland, Russell Jack Jenkins, Dana Darwish, Bridgette Kram, Kunal Karamchandani
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引用次数: 0
Abstract
Substance-use disorders (SUDs) represent a major public health concern. The increased prevalence of SUDs within the general population has led to more patients with SUD being admitted to intensive care units (ICUs) for an SUD-related condition or with SUD as a relevant comorbidity. Multiprofessional providers of critical care should be familiar with these disorders and their impact on critical illness. Management of critically ill patients with SUDs is complicated by both acute exposures leading to intoxication, the associated withdrawal syndrome(s), and the physiologic changes associated with chronic use that can cause, predispose patients to, and worsen the severity of other medical conditions. This article reviews the epidemiology of substance use in critically ill patients, discusses the identification and treatment of common intoxication and withdrawal syndromes, and provides evidence-based recommendations for the management of patients exposed to chronic use.
药物滥用障碍（SUD）是一个重大的公共卫生问题。随着 SUD 在普通人群中发病率的增加，越来越多的 SUD 患者因 SUD 相关疾病或 SUD 相关合并症而被送入重症监护病房（ICU）。重症监护的多专业提供者应熟悉这些疾病及其对重症的影响。由于急性接触导致的中毒、相关的戒断综合征以及与长期使用相关的生理变化（这些变化可能导致、使患者易患并加重其他病症的严重程度），对患有药物依赖性成瘾的重症患者的管理变得非常复杂。本文回顾了重症患者使用药物的流行病学，讨论了常见中毒和戒断综合征的识别和治疗，并为管理长期使用药物的患者提供了循证建议。
期刊介绍：
Anesthesia & Analgesia exists for the benefit of patients under the care of health care professionals engaged in the disciplines broadly related to anesthesiology, perioperative medicine, critical care medicine, and pain medicine. The Journal furthers the care of these patients by reporting the fundamental advances in the science of these clinical disciplines and by documenting the clinical, laboratory, and administrative advances that guide therapy. Anesthesia & Analgesia seeks a balance between definitive clinical and management investigations and outstanding basic scientific reports. The Journal welcomes original manuscripts containing rigorous design and analysis, even if unusual in their approach.
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