Un infarctus, mais pas du myocarde!

Pierre Robert, Benoit Lattuca
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引用次数: 0

Abstract

Pulmonary embolism (PE) is a common and serious cardiovascular disease. The management of PE patients with myocardial damage but without hemodynamic instability (intermediate/high risk) has long remained limited to anticoagulant therapy with no demonstrated positive effect of thrombolysis. In this specific population, percutaneous techniques have been developed and appear as interesting alternative in patients with clinical, biological and morphological severity criteria to reduce the evolutive risk to a more severe form and improve patients’ prognosis. We report here the case of a 49-year-old patient treated for a massive bilateral and proximal PE revealed by syncope with right ventricular impact in whom percutaneous pulmonary thrombectomy was proposed in the absence of clinical improvement after the initiation of anticoagulant therapy. The precise indications for percutaneous techniques need to be clarified in patients with intermediate/high risk PE and ongoing randomized studies should provide additional results to better identify their place in the therapeutic arsenal.

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[梗塞,但不是心肌梗塞!]
肺栓塞(PE)是一种常见的严重心血管疾病。长期以来,对有心肌损伤但无血流动力学不稳定(中/高风险)的肺栓塞患者的治疗仅限于抗凝疗法,而溶栓疗法并无明显的积极效果。针对这一特殊人群,经皮溶栓技术应运而生,对于符合临床、生物学和形态学严重程度标准的患者来说,经皮溶栓技术似乎是一种有趣的替代疗法,可降低病情恶化的风险,改善患者的预后。我们在此报告了一例 49 岁患者的病例,该患者因右心室受冲击出现晕厥而导致双侧近端大面积肺栓塞,在开始抗凝治疗后临床症状未见好转,因此建议对其进行经皮肺血栓切除术。经皮技术在中/高风险 PE 患者中的确切适应症有待明确,目前正在进行的随机研究应能提供更多结果,从而更好地确定其在治疗手段中的地位。
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来源期刊
CiteScore
0.60
自引率
0.00%
发文量
68
审稿时长
6-12 weeks
期刊介绍: Organe scientifique de référence fondé en 1951, les Annales de cardiologie et d''angéiologie abordent tous les domaines qui intéressent quotidiennement les cardiologues et les angéiologues praticiens : neurologie et radiologie vasculaires, hémostase, diabétologie, médecine interne, épidémiologie et prévention. Les Annales de cardiologie et d''angéiologie sont indexées aux grandes bases de données et publient rapidement, et en conformité avec les normes internationales de publication scientifique, des articles en français sur la pathologie cardiaque.
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