Le gradient reste élevé après mon TAVI, que faire?

Emmanuel Gall , Hakim Benamer , Dominique Fourchy , Mauro Romano , Philippe Garot , Mariama Akodad
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Abstract

Over the past two decades, transcatheter aortic valve implantation (TAVI) has become a safe and effective therapeutic option for symptomatic and severe aortic stenosis, regardless of the surgical risk spectrum. With the expansion of TAVI indications to low-risk and younger patients, it is crucial to ensure satisfactory and durable hemodynamic outcomes to guarantee transcatheter heart valve (THV) longevity. However, secondary THV dysfunction may occur, often manifested by an increased transvalvular gradient. According to VARC-3 criteria, these dysfunctions can be attributed to four main mechanisms: 1) structural valve deterioration; 2) non-structural valve dysfunction; 3) thrombosis; 4) and endocarditis. Each mechanism leads to specific abnormalities, requiring a systematic diagnostic approach and appropriate treatment. This article illustrates, through two clinical cases, the diagnosis and management of secondary transvalvular gradient elevation after TAVI.

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[如何应对 TAVR 术后梯度升高?]
在过去的二十年里,经导管主动脉瓣植入术(TAVI)已成为治疗无症状和严重主动脉瓣狭窄的一种安全有效的治疗方法,无论手术风险有多大。随着 TAVI 适应症向低风险和年轻患者扩展,确保满意和持久的血液动力学结果以保证经导管心脏瓣膜(THV)的使用寿命至关重要。然而,经导管心脏瓣膜可能会出现继发性功能障碍,通常表现为跨瓣梯度增大。根据 VARC-3 标准,这些功能障碍可归因于四种主要机制:1)结构性瓣膜退化;2)非结构性瓣膜功能障碍;3)血栓形成;4)心内膜炎。每种机制都会导致特定的异常,需要系统的诊断方法和适当的治疗。本文通过两个临床病例说明了 TAVI 术后继发性跨瓣梯度抬高的诊断和处理方法。
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来源期刊
CiteScore
0.60
自引率
0.00%
发文量
68
审稿时长
6-12 weeks
期刊介绍: Organe scientifique de référence fondé en 1951, les Annales de cardiologie et d''angéiologie abordent tous les domaines qui intéressent quotidiennement les cardiologues et les angéiologues praticiens : neurologie et radiologie vasculaires, hémostase, diabétologie, médecine interne, épidémiologie et prévention. Les Annales de cardiologie et d''angéiologie sont indexées aux grandes bases de données et publient rapidement, et en conformité avec les normes internationales de publication scientifique, des articles en français sur la pathologie cardiaque.
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