Gestational diabetes mellitus and the hearing of newborns:A nested case-control study in tropical province of China

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-08-03 DOI:10.1016/j.ijporl.2024.112056

Xiaohua Li , Weizhen Bu , Xiaojing Hu , Tianhong Han , Yan Xuan

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Abstract

Objective

This study aims to determine the association of gestational diabetes mellitus (GDM) and the results of newborn hearing screening(NHS).

Methods

A nested case-control study was conducted in a cohort of newborns who were born between June 2021 to December 2021 and underwent neonatal hearing screening.GDM was diagnosed according to the 75 g 2 h oral glucose tolerance test (OGTT) at 24–28 gestational weeks.A total of 369 pregnant women at the same hospital were individually matched in a 1:2 ratio by maternal age (±2 years), gestational age (±3 days) and sex of newborn.Chi-square test was utilized to evaluate associations between GDM and the results of NHS.

Results

Abnormal NHS results in the GDM group was more frequent than non-GDM group.When comparing the two groups (GDM case and contol), we found significant differences (p < 0.05) between them.Whereas the difference was not statistically significant (p > 0.05) by delivery modes in both case and control groups.

Conclusion

Maternal history of GDM could lead to significantly higher failling rate of NHS.

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妊娠期糖尿病与新生儿听力：中国热带省份的巢式病例对照研究。

研究目的本研究旨在确定妊娠期糖尿病（GDM）与新生儿听力筛查（NHS）结果之间的关联：方法：对2021年6月至2021年12月期间出生并接受新生儿听力筛查的新生儿进行了一项巢式病例对照研究。GDM根据孕周24-28周时的75克2小时口服葡萄糖耐量试验（OGTT）进行诊断。同一家医院的 369 名孕妇按产妇年龄（±2 岁）、胎龄（±3 天）和新生儿性别以 1:2 的比例进行了个体匹配：在比较两组（GDM 病例组和对照组）时，我们发现病例组和对照组的分娩方式存在显著差异（P 0.05）：结论：有 GDM 病史的产妇会导致 NHS 的死亡率明显升高。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.