Real-life intrinsic capacity screening data from the ICOPE-Care program

IF 17 Q1 CELL BIOLOGY Nature aging Pub Date : 2024-08-09 DOI:10.1038/s43587-024-00684-2
Philipe de Souto Barreto, Emmanuel Gonzalez-Bautista, Heike A. Bischoff-Ferrari, Vitor Pelegrim de Oliveira, Renato Gorga Bandeira de Mello, Sandrine Andrieu, Caroline Berbon, Neda Tavassoli, John R. Beard, Yves Rolland, Maria Eugenia Soto Martín, Bruno Vellas
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Abstract

The Integrated Care for Older People (ICOPE) program is a healthcare pathway that uses a screening test for intrinsic capacity (IC) as its entry point. However, real-life data informing on how IC domains cluster and change over time, as well as their clinical utility, are lacking. Using primary healthcare screening data from more than 20,000 French adults 60 years of age or older, this study identified four clusters of IC impairment: ‘Low impairment’ (most prevalent), ‘Cognition+Locomotion+Hearing+Vision’, ‘All IC impaired’ and ‘Psychology+Vitality+Vision’. Compared to individuals with ‘Low impairment’, those in the other clusters had higher likelihood of having frailty and limitations in both activities of daily living (ADL) and instrumental activities of daily living (IADL), with the strongest associations being observed for ‘All IC impaired’. This study found that ICOPE screening might be a useful tool for patient risk stratification in clinical practice, with a higher number of IC domains impaired at screening indicating a higher probability of functional decline. The Integrated Care for Older People (ICOPE) program was developed to promote a function-centered and individualized approach to healthy aging, but it is not yet widely implemented. In this study, de Souto Barreto et al. used early-stage ICOPE data collected in primary healthcare from more than 20,000 older adults to characterize patterns of intrinsic capacity impairment and associated odds of frailty and disability.

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来自 ICOPE-Care 计划的真实内在能力筛选数据。
老年人综合护理(ICOPE)计划是一种以内在能力(IC)筛查测试为切入点的医疗保健途径。然而,目前还缺乏有关 IC 领域如何聚类、随时间变化及其临床效用的真实数据。本研究利用 2 万多名 60 岁或以上法国成年人的初级医疗保健筛查数据,确定了四个 IC 损伤群组:"低损伤"(最普遍)、"认知+运动+听力+视力"、"所有 IC 损伤 "和 "心理+活力+视力"。与 "功能缺损程度低 "的人相比,其他群组中的人在日常生活活动(ADL)和工具性日常生活活动(IADL)方面出现虚弱和受限的可能性更高,其中 "所有 IC 功能缺损 "的关联性最强。这项研究发现,ICOPE 筛查可能是临床实践中对患者进行风险分层的有用工具,筛查时受损的 IC 领域越多,表明功能衰退的可能性越大。
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