Age dependent vestibulo-ocular reflex gain in video head impulse test among normal Indians.

IF 1.9 Bioinformation Pub Date : 2024-05-31 eCollection Date: 2024-01-01 DOI:10.6026/973206300200520
Saraswathi Avula, Saran Kumar, Senthi Vadivu, Mohan Kameswaran
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Abstract

Determination of the normative data of Vestibulo-Ocular Reflex gain using VHIT of all three semicircular canals (anterior, posterior, horizontal) on both sides in different age groups is of interest. This is an observational study comprised of 10 healthy individuals in each decade from less than 10 years to 80 years of both sexes making a total of 80. The study was done using the equipment SYNAPSYS VHIT ULMER with Software EVOLUTION 3.0. Mean VOR gain of each decade for all the semicircular canals is calculated and they are compared using ANOVA (Analysis of variance). In our study, percentage of patients with overt saccades is nil. Hence, in our study, the occurrence of covert saccades was insignificant as compared to the above studies. Age dependent VOR gain in normal individuals did not have any significance in our study of 80 patients performed by video head impulse test. VOR gain in our study is not affected by age. Normative data for different age groups obtained compared among different age groups showing no significant difference in Mean VOR gain. The normative values of VOR gain can be compared to patients with dizziness thus helping in determining any vestibular loss.

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正常印度人在视频头脉冲测试中的前庭眼反射增益与年龄有关。
通过使用 VHIT 测定两侧所有三个半规管(前、后、水平)的前庭-眼反射增益,确定不同年龄组的标准数据很有意义。这是一项观察性研究,从不到 10 岁到 80 岁,每个年龄段有 10 名健康人参加,男女共 80 人。研究使用 SYNAPSYS VHIT ULMER 设备和 EVOLUTION 3.0 软件进行。计算了所有半规管每个年代的平均 VOR 增益,并使用方差分析对它们进行比较。在我们的研究中,有明显囊视的患者比例为零。因此,在我们的研究中,与上述研究相比,隐性囊视的发生率微不足道。在我们通过视频头脉冲测试对 80 名患者进行的研究中,正常人的 VOR 增益与年龄无关。在我们的研究中,VOR 增益不受年龄影响。对不同年龄组的标准数据进行比较后发现,不同年龄组的平均 VOR 增益没有明显差异。VOR增益的正常值可与头晕患者进行比较,从而有助于确定是否存在前庭损失。
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Bioinformation
Bioinformation MATHEMATICAL & COMPUTATIONAL BIOLOGY-
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