[Pyoderma gangrenosum after orthopedic conservative treatment].

Revue medicale de Liege Pub Date : 2024-07-01
Morgane Pottier, Jean-Marie Servier, Vincent Migliore, Thierry Thirion, Arjen Nikkels
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Abstract

Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis. Half of the cases are associated with an immune dysfunction and are frequently triggered by pathergy such as a tissular aggression via surgery or burn wounds. A patient with ulcerative colitis presented a PG at the site of an iontophoresis patch for tendinopathy. Treatment in a specialized burn center, corticosteroid therapy and adapted local care contributed to a favourable evolution. PG remains a diagnosis of exclusion and inflammatory phenomena must be differentiated from infectious causes such as necrotizing fasciitis to initiate immunosuppressive treatment. Being rare and difficult to diagnose and to treat as well as associated with potentially severe sequelae, a multidisciplinary team is required for the management of PG.

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[骨科保守治疗后的脓皮病]。
坏疽性脓皮病(PG)是一种罕见的嗜中性皮肤病。半数病例与免疫功能失调有关,通常由嗜中性粒细胞引起,如通过手术或烧伤造成的组织侵犯。一名患有溃疡性结肠炎的患者在治疗肌腱病的离子透入贴片部位出现了 PG。在专业烧伤中心接受治疗、皮质类固醇治疗和当地护理的调整,使病情得到了良好的发展。PG 仍是一种排除性诊断,必须将炎症现象与坏死性筋膜炎等感染性病因区分开来,才能启动免疫抑制治疗。由于 PG 罕见、难以诊断和治疗,并可能伴有严重的后遗症,因此需要一个多学科团队来管理 PG。
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