Modified two-scope technique for transbronchial lung cryobiopsy of peripheral pulmonary lesions.

IF 0.8 Q4 RESPIRATORY SYSTEM Respirology Case Reports Pub Date : 2024-08-11 eCollection Date: 2024-08-01 DOI:10.1002/rcr2.1450
Sze Shyang Kho, Chan Sin Chai, Adam Malik Ismail
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Abstract

Bleeding mitigation is an important part of any transbronchial lung cryobiopsy (TBLC) procedure, either for interstitial lung disease (ILD) or peripheral pulmonary lesions (PPL). The two-scope technique has been previously described for ILD and PPL-TBLC, but it has its own limitations and technical and logistical complexities. In this case series, we describe a modified two-scope technique that enhances the conventional two-scope technique by maintaining a small equipment footprint and longer bronchoscopic vision without the need for intra-procedure switching of bronchoscopes. Three cases of PPLs were navigated by standard radial endobronchial ultrasound and biopsied with the 1.1 mm flexible ultrathin cryoprobe. All cases achieved a conclusive diagnosis with adequate specimens for immunohistochemical staining and molecular analysis; only Grade 1 bleeding reported in two cases. The challenges and limitations of this modified two-scope technique were also explored in this series.

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经支气管肺冷冻生物切片检查周围肺部病变的改良双镜技术。
减少出血是任何经支气管肺冷冻活检(TBLC)手术的重要组成部分,无论是治疗间质性肺病(ILD)还是外周肺病变(PPL)。双镜技术以前曾用于 ILD 和 PPL-TBLC,但它有其自身的局限性以及技术和后勤方面的复杂性。在本病例系列中,我们描述了一种改进的双镜技术,它通过保持较小的设备占地面积和较长的支气管镜视野而无需在术中切换支气管镜,从而增强了传统的双镜技术。通过标准径向支气管内超声对三例 PPL 进行了导航,并使用 1.1 毫米柔性超薄冷冻探针进行活检。所有病例都获得了确诊,并有足够的标本用于免疫组化染色和分子分析;只有两例报告了 1 级出血。该系列还探讨了这种改良的双镜技术所面临的挑战和局限性。
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来源期刊
Respirology Case Reports
Respirology Case Reports RESPIRATORY SYSTEM-
CiteScore
1.40
自引率
0.00%
发文量
178
审稿时长
8 weeks
期刊介绍: Respirology Case Reports is an open-access online journal dedicated to the publication of original clinical case reports, case series, clinical images and clinical videos in all fields of respiratory medicine. The Journal encourages the international exchange between clinicians and researchers of experiences in diagnosing and treating uncommon diseases or diseases with unusual presentations. All manuscripts are peer-reviewed through a streamlined process that aims at providing a rapid turnaround time from submission to publication.
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