3D Collagen Gels: A Promising Platform for Dendritic Cell Culture in Biomaterials Research

K. Shanmugam
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Abstract

The three-dimensional (3D) cell culture system has garnered significant attention in recent years as a means of studying cell behavior and tissue development, as opposed to traditional two-dimensional cultures. These systems can induce specific cell reactions, promote specific tissue functions, and serve as valuable tools for research in tissue engineering, regenerative medicine, and drug discovery. This paper discusses current developments in the field of three-dimensional cell culture and the potential applications of 3D type 1 collagen gels to enhance the growth and maturation of dendritic cells.
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三维胶原凝胶:生物材料研究中树突状细胞培养的理想平台
与传统的二维培养相比,三维(3D)细胞培养系统作为一种研究细胞行为和组织发育的手段,近年来备受关注。这些系统可以诱导特定的细胞反应,促进特定的组织功能,是研究组织工程、再生医学和药物发现的重要工具。本文讨论了三维细胞培养领域的最新发展,以及三维 1 型胶原凝胶在促进树突状细胞生长和成熟方面的潜在应用。
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