{"title":"Triterpenoids from Glochidion eriocarpum","authors":"Jin-Ni Tan, Chun-Hua Lai, Wei Wei, Qin-Gang Tan","doi":"10.1007/s10600-024-04405-4","DOIUrl":null,"url":null,"abstract":"<p>Six lupane triterpenoids (<b>1</b>–<b>6</b>), including an undescribed one, 3,23-di-<i>O</i>-isopropylidene-lup-20(29)-ene (<b>1</b>), along with two oleane triterpenoids (<b>7</b>, <b>8</b>), were isolated from the Zhuang ethnic medicinal plant Glochidion eriocarpum. Their structures were identified based on comprehensive NMR, MS, and physiochemical data analysis. Compounds <b>2</b>, <b>7</b>, and <b>8</b> significantly inhibited the production of nitride oxide (NO) of the LPS-induced RAW 264.7 cells, which may be attributed to the anti-inflammatory activity of this plant.</p>","PeriodicalId":514,"journal":{"name":"Chemistry of Natural Compounds","volume":null,"pages":null},"PeriodicalIF":0.8000,"publicationDate":"2024-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemistry of Natural Compounds","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s10600-024-04405-4","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
引用次数: 0
Abstract
Six lupane triterpenoids (1–6), including an undescribed one, 3,23-di-O-isopropylidene-lup-20(29)-ene (1), along with two oleane triterpenoids (7, 8), were isolated from the Zhuang ethnic medicinal plant Glochidion eriocarpum. Their structures were identified based on comprehensive NMR, MS, and physiochemical data analysis. Compounds 2, 7, and 8 significantly inhibited the production of nitride oxide (NO) of the LPS-induced RAW 264.7 cells, which may be attributed to the anti-inflammatory activity of this plant.
期刊介绍：
Chemistry of Natural Compounds publishes reviews and general articles about the structure of different classes of natural compounds, the chemical characteristics of botanical families, genus, and species, to establish the comparative laws and connection between physiological activity and the structure of substances.
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