From Big Data to the clinic: methodological and statistical enhancements to implement the UK Biobank imaging framework in a memory clinic

Grace Gillis, Gaurav Bhalerao, Jasmine Blane, Robert Mitchell, Pieter M Pretorius, Celeste McCracken, Thomas E Nichols, Stephen M Smith, Karla L Miller, Fidel Alfaro-Almagro, Vanessa Raymont, Lola Martos, Clare E Mackay, Ludovica Griffanti
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Abstract

Introduction The analysis tools and statistical methods used in large neuroimaging research studies differ from those applied in clinical contexts, making it unclear whether these techniques can be translated to a memory clinic setting. The Oxford Brain Health Clinic (OBHC) was established in 2020 to bridge this gap between research studies and memory clinics.
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从大数据到临床:在记忆诊所实施英国生物库成像框架的方法学和统计学改进
导言:大型神经影像研究中使用的分析工具和统计方法与临床应用中的不同,因此这些技术能否应用于记忆诊所的环境尚不清楚。牛津脑健康诊所(OBHC)成立于 2020 年,旨在缩小研究与记忆诊所之间的差距。
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