Efficacy of preoperative and postoperative medications in reducing pain after non-surgical root canal treatment: an umbrella review.

IF 3.1 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Clinical Oral Investigations Pub Date : 2024-08-14 DOI:10.1007/s00784-024-05876-z

Felipe de Souza Matos, Laura Elias Rocha, Mateus da Costa Lima, Márcia Valente de Brito Dantas, Rômulo Dias Jesuino, João Marcos da Costa Ribeiro, Walbert de Andrade Vieira, Luiz Renato Paranhos

{"title":"Efficacy of preoperative and postoperative medications in reducing pain after non-surgical root canal treatment: an umbrella review.","authors":"Felipe de Souza Matos, Laura Elias Rocha, Mateus da Costa Lima, Márcia Valente de Brito Dantas, Rômulo Dias Jesuino, João Marcos da Costa Ribeiro, Walbert de Andrade Vieira, Luiz Renato Paranhos","doi":"10.1007/s00784-024-05876-z","DOIUrl":null,"url":null,"abstract":"Objective: This study analyzed, using an umbrella review, existing systematic reviews on medications to prevent and control postoperative endodontic pain to guide professionals in choosing the most effective drug.Materials and methods: An electronic search in the PubMed (MEDLINE), LILACS, SciELO, EMBASE, Scopus, Web of Science, Cochrane Reviews, and Data Archiving and Networked Services (DANS) databases retrieved 17 systematic reviews. The study included only systematic reviews of clinical trials with or without meta-analyses evaluating effectiveness of medications in reducing pain after non-surgical endodontic treatment.Results: The evidence showed that steroidal and non-steroidal anti-inflammatory drugs and opioids effectively controlled pain within six to 24 h.Conclusions: Dexamethasone, prednisolone, paracetamol, and mainly ibuprofen provided higher postoperative pain relief. The quality of evidence of the reviews ranged from very low to high, and the risk of bias from low to high, suggesting the need for well-designed clinical trials to provide confirmatory evidence.Clinical relevance: This review emphasizes the efficacy of developing protocols for pain control after endodontic therapy.","PeriodicalId":10461,"journal":{"name":"Clinical Oral Investigations","volume":null,"pages":null},"PeriodicalIF":3.1000,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Oral Investigations","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00784-024-05876-z","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: This study analyzed, using an umbrella review, existing systematic reviews on medications to prevent and control postoperative endodontic pain to guide professionals in choosing the most effective drug.

Materials and methods: An electronic search in the PubMed (MEDLINE), LILACS, SciELO, EMBASE, Scopus, Web of Science, Cochrane Reviews, and Data Archiving and Networked Services (DANS) databases retrieved 17 systematic reviews. The study included only systematic reviews of clinical trials with or without meta-analyses evaluating effectiveness of medications in reducing pain after non-surgical endodontic treatment.

Results: The evidence showed that steroidal and non-steroidal anti-inflammatory drugs and opioids effectively controlled pain within six to 24 h.

Conclusions: Dexamethasone, prednisolone, paracetamol, and mainly ibuprofen provided higher postoperative pain relief. The quality of evidence of the reviews ranged from very low to high, and the risk of bias from low to high, suggesting the need for well-designed clinical trials to provide confirmatory evidence.

Clinical relevance: This review emphasizes the efficacy of developing protocols for pain control after endodontic therapy.

Abstract Image

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

术前和术后药物在减轻非手术根管治疗后疼痛方面的功效：综述。

目的：本研究采用总综述的方式分析了现有的牙髓术后疼痛预防和控制药物的系统综述：本研究采用总综述的方法分析了现有的预防和控制牙髓术后疼痛药物的系统综述，以指导专业人员选择最有效的药物：在 PubMed (MEDLINE)、LILACS、SciELO、EMBASE、Scopus、Web of Science、Cochrane Reviews 和 Data Archiving and Networked Services (DANS) 数据库中进行电子检索，共检索到 17 篇系统综述。该研究只纳入了评估药物在非手术根管治疗后减轻疼痛效果的临床试验的系统综述，无论是否进行了荟萃分析：证据显示，类固醇和非类固醇抗炎药物以及阿片类药物可在6至24小时内有效控制疼痛：结论：地塞米松、泼尼松龙、扑热息痛，主要是布洛芬能较好地缓解术后疼痛。综述的证据质量从很低到很高不等，偏倚风险从低到高不等，这表明需要设计良好的临床试验来提供确证证据：本综述强调了制定牙髓治疗后疼痛控制方案的有效性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Clinical Oral Investigations 医学-牙科与口腔外科

CiteScore

6.30

自引率

5.90%

发文量

484

审稿时长

3 months

期刊介绍： The journal Clinical Oral Investigations is a multidisciplinary, international forum for publication of research from all fields of oral medicine. The journal publishes original scientific articles and invited reviews which provide up-to-date results of basic and clinical studies in oral and maxillofacial science and medicine. The aim is to clarify the relevance of new results to modern practice, for an international readership. Coverage includes maxillofacial and oral surgery, prosthetics and restorative dentistry, operative dentistry, endodontics, periodontology, orthodontics, dental materials science, clinical trials, epidemiology, pedodontics, oral implant, preventive dentistiry, oral pathology, oral basic sciences and more.