Should dietary restrictions be imposed on Alzheimer's Disease patients affected by type 2 diabetes?

IF 8.3 2区 医学 Q1 Medicine Dialogues in Clinical Neuroscience Pub Date : 2024-01-01 Epub Date: 2024-08-16 DOI:10.1080/19585969.2024.2392491
Cristina Ștefănescu, Michael Davidson
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Abstract

Introduction: Antidiabetic drugs, reduction of carbohydrates intake, maintaining normal weight and physical activity are the cornerstone of diabetes 2 treatment.

Methods: This opinion article is not intended to challenge hundreds of studies unequivocally demonstrating the benefits of a healthy lifestyle including appropriate diet in controlling the consequences of T2DM. The article questions whether the benefits of dietary restrictions for the management of T2D in older adults who are already demented, are worth the potential detrimental effects on quality of life for the patients and their caregivers, as well as the effects of dietary restrictions on frailty, sarcopenia.

Discussion: However, the benefit of dietary restrictions including carbohydrates restrictions, might not manifest in elderly Alzheimer and vascular dementia patients with type 2 diabetes. On the contrary, such restrictions might hinder the patients' and caregiver's quality of life and encumber attempts to maintain normal weight in a population which tends to be underweight. Therefore, the benefit/risk ratio of dietary restriction should be weighed in this population on an individual basis.

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是否应对受 2 型糖尿病影响的阿尔茨海默病患者实施饮食限制?
导言:抗糖尿病药物、减少碳水化合物摄入量、保持正常体重和体育锻炼是治疗糖尿病 2 的基石:这篇观点文章无意质疑数百项研究明确证明的健康生活方式(包括适当饮食)对控制 T2DM 后果的益处。文章质疑的是,对已经痴呆的老年人进行饮食限制来控制 T2D 的益处,是否值得对患者及其护理人员的生活质量造成潜在的不利影响,以及饮食限制对虚弱和肌肉疏松症的影响:然而,限制饮食(包括限制碳水化合物摄入)的益处在患有 2 型糖尿病的老年痴呆症和血管性痴呆症患者身上可能并不明显。相反,这种限制可能会妨碍患者和护理人员的生活质量,并阻碍他们在体重偏低的人群中保持正常体重的努力。因此,应根据个体情况权衡限制饮食对这类人群的益处/风险比。
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来源期刊
Dialogues in Clinical Neuroscience
Dialogues in Clinical Neuroscience Medicine-Psychiatry and Mental Health
CiteScore
19.30
自引率
1.20%
发文量
1
期刊介绍: Dialogues in Clinical Neuroscience (DCNS) endeavors to bridge the gap between clinical neuropsychiatry and the neurosciences by offering state-of-the-art information and original insights into pertinent clinical, biological, and therapeutic aspects. As an open access journal, DCNS ensures accessibility to its content for all interested parties. Each issue is curated to include expert reviews, original articles, and brief reports, carefully selected to offer a comprehensive understanding of the evolving landscape in clinical neuroscience. Join us in advancing knowledge and fostering dialogue in this dynamic field.
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