Emeline Boët, Estelle Saland, Sarah Skuli, Emmanuel Griessinger, Jean-Emmanuel Sarry
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Abstract
A large body of literature highlights the importance of energy metabolism in the response of haematological malignancies to therapy. In this review, we are particularly interested in acute myeloid leukaemia, where mitochondrial metabolism plays a key role in response and resistance to treatment. We describe the new concept of mitohormesis in the response to therapy-induced stress and in the initiation of relapse in this disease.
期刊介绍：
The Comptes rendus Biologies publish monthly communications dealing with all biological and medical research fields (biological modelling, development and reproduction biology, cell biology, biochemistry, neurosciences, immunology, pharmacology, ecology, etc.).
Articles are preferably written in English. Articles in French with an abstract in English are accepted.
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