{"title":"Facile acid-mediated one-pot synthesis of dihydropyran and furan derivatives in aqueous media","authors":"Chunxia Yang, Xuefeng Xu","doi":"10.1016/j.tetlet.2024.155264","DOIUrl":null,"url":null,"abstract":"<div><p>An efficient and environmentally-friendly procedure is herein reported for the synthesis of dihydropyran and furan derivatives in aqueous media. This protocol is both facile and chemo-selective, without the use of any metal catalyst. Notably, this reaction demonstrates broad substrate scope, high efficiency, and good tolerance towards functional groups.</p></div>","PeriodicalId":438,"journal":{"name":"Tetrahedron Letters","volume":"149 ","pages":"Article 155264"},"PeriodicalIF":1.5000,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tetrahedron Letters","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0040403924003599","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
An efficient and environmentally-friendly procedure is herein reported for the synthesis of dihydropyran and furan derivatives in aqueous media. This protocol is both facile and chemo-selective, without the use of any metal catalyst. Notably, this reaction demonstrates broad substrate scope, high efficiency, and good tolerance towards functional groups.
期刊介绍:
Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.