Comparative analysis of volumetric changes between resection volume of oral tongue cancer and post operative volume of radial forearm flaps.

IF 3.1 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Clinical Oral Investigations Pub Date : 2024-08-25 DOI:10.1007/s00784-024-05885-y

Matthias Zirk, Mina Niknazemi, Maximilian Riekert, Matthias Kreppel, Christian Linz, Max-Philipp Lentzen

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Abstract

Objectives: This study investigates the relationship between the total volume of oral tongue cancer pre-operatively and the RFFF volume post-operatively.

Materials and methods: A total of 52 DICOM imaging datasets (CT or MRI) of 26 patients were included in this study. The volume of the desired structure was quantified using semi-automatic segmentation using the software ITK-SNAP. All extracted measurements were validated by two further clinicians at separate instances.

Results: The variation of MeanVolTu can be predicted by MeanVolFlap moderately reliable with 59.1% confidence (R-Qua: 0.591). ANOVA Testing to represent how well the regression line fits the data, resulted in the overall regression model being statistically significant in predicting the MeanVolTu (p < 0.001). The flap volume may be predicted using the following algorithm: MeanVolFlap0 = 3241,633 + 1, 322 * MeanVolTu.

Conclusion: The results of this study show positive correlation between tumor volume and flap volume, highlighting the significance of efficient flap planning with increasing tumor volume. A larger extraction volume of the radial forearm free flap from the donor site compromises the forearm more, thus increasing the probability of post-operative complications.

Clinical relevance: Radial forearm free flap design in accordance with its corresponding 3D tumor volume.

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口腔舌癌切除体积与桡侧前臂皮瓣术后体积变化的对比分析。

研究目的本研究探讨了口腔舌癌术前总体积与术后 RFFF 体积之间的关系：本研究共纳入了 26 名患者的 52 个 DICOM 成像数据集（CT 或 MRI）。使用 ITK-SNAP 软件进行半自动分割，对所需结构的体积进行量化。所有提取的测量值均由另外两名临床医生分别进行了验证：结果：MeanVolTu 的变化可通过 MeanVolFlap 预测，可信度为 59.1%（R-Qua：0.591）。方差分析测试代表了回归线与数据的拟合程度，结果表明整体回归模型在预测 MeanVolTu 方面具有显著的统计学意义（p 结论：MeanVolFlap 预测 MeanVolTu 的变化具有较高的可信度（R-Qua：0.591）：本研究结果表明，肿瘤体积与皮瓣体积呈正相关，突出了随着肿瘤体积的增大，高效皮瓣规划的重要性。从供体部位提取的前臂桡侧游离皮瓣体积越大，对前臂的损害越大，从而增加了术后并发症的概率：临床意义：根据相应的三维肿瘤体积设计前臂桡侧游离皮瓣。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Oral Investigations 医学-牙科与口腔外科

CiteScore

6.30

自引率

5.90%

发文量

484

审稿时长

3 months

期刊介绍： The journal Clinical Oral Investigations is a multidisciplinary, international forum for publication of research from all fields of oral medicine. The journal publishes original scientific articles and invited reviews which provide up-to-date results of basic and clinical studies in oral and maxillofacial science and medicine. The aim is to clarify the relevance of new results to modern practice, for an international readership. Coverage includes maxillofacial and oral surgery, prosthetics and restorative dentistry, operative dentistry, endodontics, periodontology, orthodontics, dental materials science, clinical trials, epidemiology, pedodontics, oral implant, preventive dentistiry, oral pathology, oral basic sciences and more.