A 79-Year-Old Woman With Worsening Headaches and Pachymeningeal Enhancement: A Case Report From the National Multiple Sclerosis Society Case Conference Proceedings.

IF 7.8 1区 医学 Q1 CLINICAL NEUROLOGY Neurology® Neuroimmunology & Neuroinflammation Pub Date : 2024-11-01 Epub Date: 2024-08-27 DOI:10.1212/NXI.0000000000200308
Manali S Sheth, David E Hale, Justin C Mcarthur, Scott S Zamvil, Myla D Goldman, Claire Riley, Tanuja Chitnis
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Abstract

A 79-year-old woman presented with subacutely worsening headaches and right arm weakness. MRI showed diffuse pachymeningeal enhancement. Serologic workup revealed elevated erythrocyte sedimentation rate and C-reactive protein. CSF demonstrated elevated opening pressure, a lymphocytic pleocytosis, and elevated protein. We discuss our differential diagnosis and distinguish between 2 overlapping clinical entities.

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一位 79 岁的妇女头痛加剧并伴有门脉增强:全国多发性硬化症协会病例会议论文集中的病例报告。
一名 79 岁的妇女因亚急性头痛和右臂无力而就诊。核磁共振成像显示弥漫性脑膜增强。血清学检查显示红细胞沉降率和 C 反应蛋白升高。脑脊液显示开口压升高、淋巴细胞增多和蛋白升高。我们讨论了鉴别诊断,并区分了两种重叠的临床实体。
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来源期刊
CiteScore
15.60
自引率
2.30%
发文量
219
审稿时长
8 weeks
期刊介绍: Neurology Neuroimmunology & Neuroinflammation is an official journal of the American Academy of Neurology. Neurology: Neuroimmunology & Neuroinflammation will be the premier peer-reviewed journal in neuroimmunology and neuroinflammation. This journal publishes rigorously peer-reviewed open-access reports of original research and in-depth reviews of topics in neuroimmunology & neuroinflammation, affecting the full range of neurologic diseases including (but not limited to) Alzheimer's disease, Parkinson's disease, ALS, tauopathy, and stroke; multiple sclerosis and NMO; inflammatory peripheral nerve and muscle disease, Guillain-Barré and myasthenia gravis; nervous system infection; paraneoplastic syndromes, noninfectious encephalitides and other antibody-mediated disorders; and psychiatric and neurodevelopmental disorders. Clinical trials, instructive case reports, and small case series will also be featured.
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