Blue Dye-Assisted Intraoperative Optical Coherence Tomography for Macular Surgery.

IF 2.1 4区医学 Q2 OPHTHALMOLOGY Ophthalmologica Pub Date : 2024-08-27 DOI:10.1159/000541056

Marco Pellegrini, Ginevra Adamo, Laura Sarti, Pietro Maria Talli, Francesco Nasini, Marco Mura

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Abstract

Introduction: The purpose of this study was to evaluate whether vital blue dyes could enhance the contrast of intraoperative optical coherence tomography (OCT) during macular surgery.

Methods: Consecutive patients undergoing elective pars plana vitrectomy for vitreomacular interface disorders were enrolled. Intraoperative OCT was performed with the Artevo 800 microscope (Carl Zeiss Meditec AG, Jena, Germany) before and after injection of 0.2 mL of Trypan Blue and Brilliant Blue G Ophthalmic Solution. The OCT contrast ratio was measured with ImageJ, while the overall scan quality was subjectively classified using a 4-point scale.

Results: Ten eyes of 10 patients were enrolled in the study. The OCT contrast ratio was 9.39 ± 5.35 without blue dye and significantly improved to 14.31 ± 10.50 after blue dye injection (p = 0.027). The percentage of patients with a grade 4 scan quality also significantly improved (from 40% without blue dye to 90% with blue dye injection; p = 0.012).

Conclusion: The use of blue dyes during intraoperative OCT is an effective strategy for improving contrast and scan quality without affecting the surgical time and workflow.

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用于黄斑手术的蓝染料辅助术中光学相干断层扫描。

简介本研究旨在评估生命蓝染料能否增强黄斑手术中术中 OCT 的对比度：方法：连续招募因玻璃体黄斑界面紊乱而接受选择性玻璃体旁切除术的患者。在注射 0.2 mL 胰酶蓝和亮蓝 G 眼科溶液之前和之后，使用 Artevo 800 显微镜（卡尔蔡司 Meditec AG，德国耶拿，Jena）进行术中 OCT 扫描。OCT 对比度用 ImageJ 进行测量，整体扫描质量用 4 分制进行主观评分：结果：10 名患者的 10 只眼睛参加了研究。未注射蓝色染料时，OCT 对比度为 9.39 ± 5.35，注射蓝色染料后，对比度显著提高至 14.31 ± 10.50（P = 0.027）。扫描质量为 4 级的患者比例也明显提高（从未用到蓝色染料时的 40% 提高到注射蓝色染料后的 90%；P = 0.012）：结论：术中 OCT 使用蓝色染料是提高对比度和扫描质量的有效策略，且不会影响手术时间和工作流程。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ophthalmologica 医学-眼科学

CiteScore

5.10

自引率

3.80%

发文量

审稿时长

3 months

期刊介绍： Published since 1899, ''Ophthalmologica'' has become a frequently cited guide to international work in clinical and experimental ophthalmology. It contains a selection of patient-oriented contributions covering the etiology of eye diseases, diagnostic techniques, and advances in medical and surgical treatment. Straightforward, factual reporting provides both interesting and useful reading. In addition to original papers, ''Ophthalmologica'' features regularly timely reviews in an effort to keep the reader well informed and updated. The large international circulation of this journal reflects its importance.