Gouty Tophus Erodes Nasal Bone But Presents as Painless Hump.

IF 1 4区 医学 Q3 SURGERY Journal of Craniofacial Surgery Pub Date : 2024-09-02 DOI:10.1097/SCS.0000000000010598
Hou-Fu Xia, Ming-Yang Yu, Si-Rui Ma, Zi-Li Yu, Jun Jia
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Abstract

A 32-year-old male presented with a painless swelling on his nasal dorsum, persisting for over 3 months. He reported a gradual increase in the size of the mass, with no identifiable triggers except occasional skin redness. He denied nosebleeds, rhinorrhea, nasal obstruction, trauma, prior surgery, or spontaneous pain. His medical history revealed gout, managed with colchicine and diclofenac. Despite dietary and pharmaceutical interventions, he continued to have bouts of hyperuricemia, with blood uric acid levels measuring 739 μmol/L. Multiple tophi were evident, especially on the left first metatarsophalangeal joint (Figure 1A). Examination revealed an irregularly shaped, immobile, hard swelling at the nasal radix, measuring 3 cm×2 cm. Computerized tomography (CT) imaging of the nose showed bilateral nasal bone destruction from the lesion. Given its impact on the patient's appearance and his history of gout, the mass was initially diagnosed as unusual gouty tophus. The patient requested surgical removal of the lesion, and the dissection revealed a mass partly encased by a capsule-like connective tissue adherent to the nasal bone. As the lesion damaged the nasal bone, removal of the lesion led to defect of nasal bone. After an extensive rinse of the surgery site, the incision was sutured.

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痛风性鼻赘侵蚀鼻骨,但表现为无痛性驼峰。
一名 32 岁的男性因鼻背无痛性肿胀就诊,已持续 3 个多月。他说肿块逐渐增大,除了偶尔皮肤发红外,没有可识别的诱因。他否认流鼻血、鼻出血、鼻塞、外伤、手术或自发性疼痛。病史显示他患有痛风,曾用秋水仙碱和双氯芬酸治疗。尽管采取了饮食和药物干预措施,但他仍不断出现高尿酸血症,血尿酸水平达到 739 μmol/L。多处丘疹明显,尤其是左侧第一跖趾关节(图 1A)。检查发现鼻根部有一个形状不规则、无法移动的硬肿物,大小为 3 厘米×2 厘米。鼻部计算机断层扫描(CT)成像显示,病变造成双侧鼻骨破坏。考虑到肿块对患者外貌的影响以及他的痛风病史,肿块最初被诊断为不寻常的痛风性鼻赘。患者要求手术切除病灶,解剖后发现肿块部分被粘附在鼻骨上的囊状结缔组织包裹。由于病变损害了鼻骨,切除病变导致鼻骨缺损。对手术部位进行广泛冲洗后,缝合了切口。
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来源期刊
CiteScore
1.70
自引率
11.10%
发文量
968
审稿时长
1.5 months
期刊介绍: ​The Journal of Craniofacial Surgery serves as a forum of communication for all those involved in craniofacial surgery, maxillofacial surgery and pediatric plastic surgery. Coverage ranges from practical aspects of craniofacial surgery to the basic science that underlies surgical practice. The journal publishes original articles, scientific reviews, editorials and invited commentary, abstracts and selected articles from international journals, and occasional international bibliographies in craniofacial surgery.
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