Vegan Glucosamine versus Crustacean Glucosamine in Osteoarthritis: Choosing the Correct One During Clinical Practice.

Q4 Medicine Mediterranean Journal of Rheumatology Pub Date : 2024-04-23 eCollection Date: 2024-06-01 DOI:10.31138/mjr.201223.vgv
Hitesh Verma
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Abstract

The present commentary critically evaluates the role of glucosamine in joint health, specifically exploring the potential of vegan glucosamine as an alternative of crustacean glucosamine. While acknowledging glucosamine's established benefits in managing osteoarthritis, this commentary underscores concern regarding the limited data supporting the clinical use of vegan glucosamine. Methodological flaws in the bioequivalence study, lax quality parameters, and the absence of safety data for E. coli-derived vegan glucosamine are highlighted. The commentary calls for caution in endorsing vegan glucosamine for osteoarthritis patients, stressing the need for further research and a thorough evaluation of its efficacy and safety before widespread clinical adoption.

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骨关节炎中的素食葡萄糖胺与甲壳动物葡萄糖胺:在临床实践中正确选择。
本评论批判性地评估了葡萄糖胺在关节健康中的作用,特别探讨了素食葡萄糖胺作为甲壳类葡萄糖胺替代品的潜力。本评论承认氨基葡萄糖在治疗骨关节炎方面具有公认的益处,但也强调了对支持临床使用素食氨基葡萄糖的有限数据的担忧。其中强调了生物等效性研究中的方法缺陷、质量参数不严格以及大肠杆菌衍生的素食氨基葡萄糖缺乏安全性数据。评论呼吁在认可骨关节炎患者使用纯素氨基葡萄糖时要谨慎,强调在临床广泛使用前需要进一步研究并对其疗效和安全性进行全面评估。
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来源期刊
CiteScore
2.00
自引率
0.00%
发文量
42
审稿时长
8 weeks
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