Rectal perforation following SpaceOAR placement combined with permanent prostate brachytherapy

Q4 Medicine IJU Case Reports Pub Date : 2024-08-13 DOI:10.1002/iju5.12769

Masashi Morita, Mayo Tanabe, Chisa Kinugawa, Saori Nakamura, Satoshi Amano, Kota Nishimura, Jin Yamatoya, Tetsuo Noguchi, Aya Hiramatsu, Takashi Fukagai

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Abstract

Introduction

We report a case of rectal perforation following SpaceOAR placement utilized with iodine-125 low-dose-rate brachytherapy for prostate cancer.

Case presentation

A 65-year-old patient with localized prostate cancer underwent SpaceOAR placement following LDR-BT. No significant issues occurred with the SpaceOAR procedure, and no abnormalities were found on the next day's T2-weighted magnetic resonance imaging. Two weeks later, a colonoscopy was performed due to mucus stools revealing rectal perforation attributed to SpaceOAR. By maintaining Macrogol 4000 and a low residue diet, the perforation healed within 6 months.

Conclusion

Rectal ulcers and perforations are the most common severe adverse events from SpaceOAR placement. Effective management strategies are crucial since complications can't be entirely avoided, even with skilled surgeons.

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SpaceOAR 置入术联合永久性前列腺近距离放射治疗后出现直肠穿孔。

导言：我们报告了一例利用碘-125 低剂量近距离放射治疗前列腺癌的 SpaceOAR 置入术后直肠穿孔的病例：一名 65 岁的局部前列腺癌患者在 LDR-BT 后接受了 SpaceOAR 置入术。SpaceOAR 手术未出现重大问题，第二天的 T2 加权磁共振成像也未发现异常。两周后，由于粘液便显示直肠穿孔，患者接受了结肠镜检查。通过坚持 Macrogol 4000 和低渣饮食，穿孔在 6 个月内愈合：直肠溃疡和穿孔是放置 SpaceOAR 最常见的严重不良反应。结论：直肠溃疡和穿孔是 SpaceOAR 置入术后最常见的严重不良反应，有效的处理策略至关重要，因为即使是技术娴熟的外科医生也无法完全避免并发症的发生。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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