Treatment of a Congenital Melocytic Giant Naevi at Age 39 Using Split-Thickness Skin Graft Over an Artificial Dermal Scaffold Through 2-Step Operation: A Novel Technique and Literature Review.

Eplasty Pub Date : 2024-08-09 eCollection Date: 2024-01-01
Merve Akin, Ali Emre Akgün, Huriye Bilge Tuncer
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Abstract

Congenital melanocytic nevus is a benign proliferation seen from birth. However, malignant transformation can be observed in later ages, so the removal of especially large and giant nevi is recommended during childhood. Nevertheless, there are no cases reported in the literature regarding excision of giant congenital melanocytic nevi in advanced age. This article presents the first case of a 39-year-old patient with a giant congenital melanocytic nevus covering 10% of the total body surface area, who underwent treatment with a 2-step operation. The nevus was located on the back, covering 10% of the total body surface area. The patient underwent en-bloc excision. A bilayer dermal matrix was applied over the fascia. Subsequently, a split-thickness skin graft was applied to the entire area. Full re-epithelialization was achieved within a total of 35 days. Thanks to the applied dermal scaffold, the area became pliable.

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通过两步手术使用人工真皮支架上的裂厚皮肤移植治疗 39 岁先天性黑素细胞巨痣:一项新技术和文献综述。
先天性黑素细胞痣是一种良性增生,从出生时就可以看到。然而,恶性转化可在晚年出现,因此建议在儿童时期切除特别大和巨大的痣。然而,文献中还没有关于在晚年切除巨大先天性黑素细胞痣的病例。本文首次介绍了一例 39 岁的先天性巨型黑素细胞痣患者,该痣占全身面积的 10%,患者接受了两步手术治疗。痣位于背部,占体表总面积的 10%。患者接受了全切术。在筋膜上覆盖了一层双层真皮基质。随后,在整个区域进行了分层厚皮移植。在总共 35 天的时间里,皮肤完全重新上皮化。由于使用了真皮支架,该区域变得柔韧。
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