Application of thioamides as sulfur sources to the synthesis of thieno[2,3-b]quinoxalines

IF 1.5 4区 化学 Q3 CHEMISTRY, ORGANIC Tetrahedron Letters Pub Date : 2024-08-28 DOI:10.1016/j.tetlet.2024.155279
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Abstract

An efficient synthesis of thieno[2,3-b]quinoxalines by thiolative cyclization of 2-chloro-3-(phenylethynyl)quinoxalines using primary thioamides as sulfur sources has been proposed. The reactions provided moderate to good yields under mild conditions.

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硫代酰胺作为硫源在合成噻吩并[2,3-b]喹喔啉中的应用
以伯硫代酰胺为硫源,通过 2-氯-3-(苯乙炔基)喹喔啉的硫醇环化反应,提出了一种高效合成噻吩并[2,3-b]喹喔啉的方法。在温和的条件下,反应提供了中等到良好的产率。
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来源期刊
Tetrahedron Letters
Tetrahedron Letters 化学-有机化学
CiteScore
3.50
自引率
5.60%
发文量
521
审稿时长
28 days
期刊介绍: Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.
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