{"title":"Association between dietary vitamin E intake and constipation: NHANES 2005-2010.","authors":"Junfeng Cai, Danqing Li, Ruijun Xie, Xiaoling Yu, Yuning Wu, Feng Sun, Chenxiong Zhang","doi":"10.3389/fnut.2024.1426280","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>This investigation aimed to analyze the association between dietary vitamin E intake and constipation prevalence among United States adults.</p><p><strong>Methods: </strong>Utilizing data from the National Health and Nutrition Examination Survey (NHANES), this cross-sectional study assessed vitamin E intake through 24-h dietary recall and defined constipation based on the Bristol Stool Form Scale (BSFS). Logistic regression models were employed to evaluate the relationship between vitamin E intake and constipation, with results presented as odds ratios (ORs) and 95% confidence intervals (CIs). Stratified analyses were conducted based on covariates such as age, and restricted cubic spline (RCS) models were generated to explore the potential linear or non-linear association.</p><p><strong>Results: </strong>Individuals experiencing constipation exhibited lower vitamin E intake compared to those without constipation. Weighted multivariate logistic regression models demonstrated a negative correlation between vitamin E intake and constipation risk, even after adjusting for potential confounding variables. Further RCS analysis revealed a statistically significant non-linear inverse relationship between vitamin E intake and constipation risk (<i>p</i>-value for non-linearity = 0.0473).</p><p><strong>Conclusion: </strong>Our findings suggest an independent inverse association between vitamin E intake and constipation prevalence in United States adults. Prospective research is needed to validate these observations.</p>","PeriodicalId":12473,"journal":{"name":"Frontiers in Nutrition","volume":null,"pages":null},"PeriodicalIF":4.0000,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11368839/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in Nutrition","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.3389/fnut.2024.1426280","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
引用次数: 0
Abstract
Background: This investigation aimed to analyze the association between dietary vitamin E intake and constipation prevalence among United States adults.
Methods: Utilizing data from the National Health and Nutrition Examination Survey (NHANES), this cross-sectional study assessed vitamin E intake through 24-h dietary recall and defined constipation based on the Bristol Stool Form Scale (BSFS). Logistic regression models were employed to evaluate the relationship between vitamin E intake and constipation, with results presented as odds ratios (ORs) and 95% confidence intervals (CIs). Stratified analyses were conducted based on covariates such as age, and restricted cubic spline (RCS) models were generated to explore the potential linear or non-linear association.
Results: Individuals experiencing constipation exhibited lower vitamin E intake compared to those without constipation. Weighted multivariate logistic regression models demonstrated a negative correlation between vitamin E intake and constipation risk, even after adjusting for potential confounding variables. Further RCS analysis revealed a statistically significant non-linear inverse relationship between vitamin E intake and constipation risk (p-value for non-linearity = 0.0473).
Conclusion: Our findings suggest an independent inverse association between vitamin E intake and constipation prevalence in United States adults. Prospective research is needed to validate these observations.
背景：这项调查旨在分析美国成年人膳食维生素 E 摄入量与便秘发生率之间的关系：这项调查旨在分析美国成年人膳食中维生素 E 摄入量与便秘发生率之间的关系：这项横断面研究利用美国国家健康与营养调查（NHANES）的数据，通过24小时膳食回顾评估维生素E的摄入量，并根据布里斯托粪便形式量表（BSFS）定义便秘。研究采用逻辑回归模型评估维生素 E 摄入量与便秘之间的关系，结果以几率比（OR）和 95% 置信区间（CI）表示。根据年龄等协变量进行了分层分析，并生成了限制性立方样条线（RCS）模型，以探索潜在的线性或非线性关联：结果：与无便秘者相比，便秘者的维生素 E 摄入量较低。加权多变量逻辑回归模型显示，即使在调整了潜在的混杂变量后，维生素 E 摄入量与便秘风险之间仍存在负相关。进一步的 RCS 分析表明，维生素 E 摄入量与便秘风险之间存在具有统计学意义的非线性反比关系（非线性的 p 值 = 0.0473）：我们的研究结果表明，在美国成年人中，维生素 E 摄入量与便秘发生率之间存在独立的反向关系。需要进行前瞻性研究来验证这些观察结果。
期刊介绍：
No subject pertains more to human life than nutrition. The aim of Frontiers in Nutrition is to integrate major scientific disciplines in this vast field in order to address the most relevant and pertinent questions and developments. Our ambition is to create an integrated podium based on original research, clinical trials, and contemporary reviews to build a reputable knowledge forum in the domains of human health, dietary behaviors, agronomy & 21st century food science. Through the recognized open-access Frontiers platform we welcome manuscripts to our dedicated sections relating to different areas in the field of nutrition with a focus on human health.
Specialty sections in Frontiers in Nutrition include, for example, Clinical Nutrition, Nutrition & Sustainable Diets, Nutrition and Food Science Technology, Nutrition Methodology, Sport & Exercise Nutrition, Food Chemistry, and Nutritional Immunology. Based on the publication of rigorous scientific research, we thrive to achieve a visible impact on the global nutrition agenda addressing the grand challenges of our time, including obesity, malnutrition, hunger, food waste, sustainability and consumer health.
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