EFFECT OF XIAOYAO PILLS COMBINED WITH ALENDRONATE ON BONE DENSITY IN POSTMENOPAUSAL PATIENTS WITH OSTEOPOROSIS.

Abstract

Objective: The aim of the study was to explore the effect of Xiaoyao Pills combined with alendronate on bone density in postmenopausal patients with osteoporosis.

Methods: The data of postmenopausal osteoporosis patients admitted to Taizhou Hospital of Traditional Chinese Medicine from January 2022 to January 2023 were retrospectively collected. According to the treatment method, patients were randomly divided into study group and control group. Finally, 54 cases were selected for each group. The study group was treated with Xiaoyao Pills combined with alendronate sodium, while the control group was treated with alendronate sodium alone. The femoral neck bone density of the two groups of patients was observed.

Results: Compared with before treatment, the bone mineral density of both groups of patients increased significantly 6 months and 12 months after treatment (P＜0.05). Comparing the bone density of the two groups of patients before treatment, the difference was not statistically significant [(0.58±0.06) g/ cm² vs. (0.60±0.08) g/cm², P=0.486]. Compared with the control group, the bone density of the study group increased significantly after 6 months of treatment [(0.69±0.08)g/cm² vs. (0.60±0.08)g/cm²].

Conclusion: Xiaoyao Pills combined with alendronate can improve bone density in postmenopausal patients with osteoporosis.