Wei Chen, Wanxiang Wang, Run Wu, Haiping Zhou, Pingbing Yu
{"title":"Intermolecular Sulfenoamination of Alkenes with Free-Thiols and NIS to Access β-Succinimide Sulfides.","authors":"Wei Chen, Wanxiang Wang, Run Wu, Haiping Zhou, Pingbing Yu","doi":"10.1002/asia.202400945","DOIUrl":null,"url":null,"abstract":"<p><p>A convenient and practical multicomponent strategy for the sulfenoamination of alkenes was realized, which using free-thiols as the sulfur-reagent, NIS both as radical initiator and an N-nucleophile. This protocol excellent in terms of transition-metal-free, good functional group tolerance, easily available substrates and facile scale-up. And provided a direct- and general way to synthesize various β-succinimide sulfides with high regioselectivity.</p>","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":null,"pages":null},"PeriodicalIF":3.5000,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemistry - An Asian Journal","FirstCategoryId":"1","ListUrlMain":"https://doi.org/10.1002/asia.202400945","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
A convenient and practical multicomponent strategy for the sulfenoamination of alkenes was realized, which using free-thiols as the sulfur-reagent, NIS both as radical initiator and an N-nucleophile. This protocol excellent in terms of transition-metal-free, good functional group tolerance, easily available substrates and facile scale-up. And provided a direct- and general way to synthesize various β-succinimide sulfides with high regioselectivity.
期刊介绍:
Chemistry—An Asian Journal is an international high-impact journal for chemistry in its broadest sense. The journal covers all aspects of chemistry from biochemistry through organic and inorganic chemistry to physical chemistry, including interdisciplinary topics.
Chemistry—An Asian Journal publishes Full Papers, Communications, and Focus Reviews.
A professional editorial team headed by Dr. Theresa Kueckmann and an Editorial Board (headed by Professor Susumu Kitagawa) ensure the highest quality of the peer-review process, the contents and the production of the journal.
Chemistry—An Asian Journal is published on behalf of the Asian Chemical Editorial Society (ACES), an association of numerous Asian chemical societies, and supported by the Gesellschaft Deutscher Chemiker (GDCh, German Chemical Society), ChemPubSoc Europe, and the Federation of Asian Chemical Societies (FACS).