Trends on Prevalence, All-Cause Mortality, and Survival Status of Dementia Patients in Rural China Based on Pooling Analysis.

IF 2.6 3区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH International Journal of Public Health Pub Date : 2024-08-22 eCollection Date: 2024-01-01 DOI:10.3389/ijph.2024.1606786

Kang Huo, Suhang Shang, Jin Wang, Chen Chen, Liangjun Dang, Ling Gao, Shan Wei, Lingxia Zeng, Qiumin Qu

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Abstract

Objectives: No study has reported secular trends in dementia prevalence, all-cause mortality, and survival status in rural China.

Methods: We established two cohorts (XRRCC1 and XRRCC2) in the same region of China, 17 years apart, to compare dementia prevalence, all-cause mortality, and survival status, and performed regression analysis to identify associated factors.

Results: Dementia prevalence was 3.49% in XRRCC1 and 4.25% in XRRCC2, with XRRCC2 showing a significantly higher prevalence (OR = 1.79, 95%CI: 1.2-2.65). All-cause mortality rates for dementia patients were 62.0% in XRRCC1 and 35.7% in XRRCC2. Mortality in the normal population of XRRCC2 decreased by 66% compared to XRRCC1, mainly due to improved survival rates in women with dementia. Dementia prevalence was positively associated with age >65, spouse-absent status, and stroke, and negatively associated with ≥6 years of education.

Conclusion: Dementia prevalence in rural China increased over 17 years, while mortality decreased. Major risk factors include aging, no spouse, and stroke, with higher education offering some protection.

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基于汇集分析的中国农村痴呆症患者患病率、全因死亡率和生存状况的趋势。

研究目的方法：我们在中国同一地区建立了两个队列（XRRCC1 和 XRRCC2），相隔 17 年：我们在中国同一地区建立了两个队列（XRRCC1 和 XRRCC2），相隔 17 年，比较痴呆患病率、全因死亡率和生存状况，并进行回归分析以确定相关因素：XRRCC1和XRRCC2的痴呆患病率分别为3.49%和4.25%，其中XRRCC2的痴呆患病率明显更高（OR=1.79，95%CI：1.2-2.65）。痴呆症患者的全因死亡率在 XRRCC1 中为 62.0%，在 XRRCC2 中为 35.7%。与 XRRCC1 相比，XRRCC2 正常人群的死亡率降低了 66%，这主要是因为痴呆症女性患者的存活率提高了。痴呆症患病率与年龄大于 65 岁、无配偶和中风呈正相关，与受教育时间≥6 年呈负相关：结论：中国农村痴呆症患病率在 17 年间有所上升，而死亡率有所下降。主要风险因素包括高龄、无配偶和中风，而高学历则提供了一定的保护。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Public Health 医学-公共卫生、环境卫生与职业卫生

CiteScore

4.20

自引率

2.20%

发文量

269

审稿时长

12 months

期刊介绍： The International Journal of Public Health publishes scientific articles relevant to global public health, from different countries and cultures, and assembles them into issues that raise awareness and understanding of public health problems and solutions. The Journal welcomes submissions of original research, critical and relevant reviews, methodological papers and manuscripts that emphasize theoretical content. IJPH sometimes publishes commentaries and opinions. Special issues highlight key areas of current research. The Editorial Board''s mission is to provide a thoughtful forum for contemporary issues and challenges in global public health research and practice.